In-vitro inhibitory effect of maternal breastmilk components on rotavirus vaccine replication and association with infant seroconversion to live oral rotavirus vaccine.

Author: BosomprahSamuel, ChilengiRoma, ChisengaCaroline C, KazimbayaKatayi Mwila, LabanNatasha Makabilo, MunsakaSody, PermarSallie R, PhiriCynthia Mubanga, SimuyandiMichelo

Paper Details 
Original Abstract of the Article :
Despite contributing to a significant reduction in rotavirus associated diarrhoea in highly burdened low- and middle-income countries, live attenuated, oral rotavirus vaccines have lower immunogenicity and efficacy in these settings in comparison to more developed countries. Breastmilk has been impl...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654788/

データ提供:米国国立医学図書館(NLM)

Exploring the Impact of Breastmilk on Rotavirus Vaccine Efficacy

This study delves into the fascinating world of immunology and the intricate interplay between breastmilk and rotavirus vaccines, a journey akin to traversing the vast desert of scientific exploration. It aims to uncover the reasons behind the lower immunogenicity and efficacy of rotavirus vaccines in certain regions, particularly in low- and middle-income countries. Focusing on the potential influence of breastmilk, the study explores the inhibitory effects of maternal antibodies and other breastmilk components on rotavirus vaccine replication. This research is like a treasure hunt, seeking to uncover the hidden mechanisms that influence vaccine efficacy and potentially reveal strategies for enhancing its effectiveness.

Unlocking the Secrets of Breastmilk

The study's findings reveal the potential role of breastmilk components in impacting the effectiveness of rotavirus vaccines. By exploring the inhibitory effects of breastmilk on vaccine replication, this research provides valuable insights into the complex interplay between maternal factors and vaccine responses. This knowledge could pave the way for developing strategies to enhance vaccine efficacy in regions where it is lower, ultimately protecting more infants from rotavirus infection.

The Power of Mother's Milk

Breastmilk is a remarkable natural elixir, a gift from mother to child that provides nourishment and protection. This research sheds light on the potential role of breastmilk in influencing the efficacy of vaccines, a testament to its complex and multifaceted benefits. Understanding these intricate connections can lead to better strategies for supporting infant health and well-being, especially in regions where vaccine efficacy may be lower.

Dr. Camel's Conclusion

This research is like a hidden oasis in the vast desert of medical knowledge, revealing the power of breastmilk in influencing vaccine efficacy. It emphasizes the importance of understanding the complex interplay between maternal factors and vaccine responses, highlighting the need for further exploration in this field. The study's findings are a testament to the enduring value of breastmilk as a vital component of infant health and well-being.

Date :
  1. Date Completed 2020-12-17
  2. Date Revised 2023-11-13
Further Info :

Pubmed ID

33170860

DOI: Digital Object Identifier

PMC7654788

Related Literature

SNS
PICO Info
in preparation
Languages

English

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