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[Clinical and Fundamental Approach for Chemotherapy-induced Adverse Effect Attenuation by Oncology Pharmacy Specialists].

Author: SaitoYoshitaka

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This study evaluates the efficacy of long-term pharmaceutical care in outpatient chemotherapy and the nephroprotective effects of magnesium (Mg) against cisplatin-induced nephrotoxicity (CIN). The results demonstrate the benefit of pharmaceutical interventions in mitigating painful symptoms and reducing CIN. Mg premedication was found to be effective in attenuating CIN without affecting adverse effects or response rate.
Paper Details　
Original Abstract of the Article :
Management of chemotherapy-induced adverse effects and the associated pharmaceutical interventions as well as supportive care evidence creation are the most important responsibilities of oncology pharmacists. We have evaluated the (1) efficacy of long-term and successive pharmaceutical care in outpa...See full text at original site
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引用元：
https://doi.org/10.1248/yakushi.20-00122

データ提供：米国国立医学図書館（NLM）

Oncology Pharmacists: Guardians of Chemotherapy Safety

Navigating the complex landscape of cancer treatment requires a multidisciplinary approach, and oncology pharmacists play a crucial role in ensuring the safety and effectiveness of chemotherapy. This study explores the contributions of oncology pharmacists in managing chemotherapy-induced adverse effects and providing supportive care.

Pharmaceutical Care in Outpatient Chemotherapy

The study found that long-term pharmaceutical care provided by oncology pharmacists significantly improved the safety and tolerability of outpatient chemotherapy. The pharmacists' interventions, which included personalized medication adjustments and supportive care strategies, were highly effective in attenuating painful symptoms and improving overall patient outcomes.

Protecting Kidney Health

The researchers also investigated the nephroprotective effects of magnesium (Mg) in mitigating cisplatin-induced nephrotoxicity (CIN). They found that premedication with Mg effectively reduced CIN frequency and serum creatinine elevation without compromising the efficacy of chemotherapy. This finding emphasizes the importance of proactive measures to protect vulnerable organs during cancer treatment.

Dr.Camel's Conclusion

This study highlights the invaluable role of oncology pharmacists in optimizing cancer care. Their expertise in medication management, supportive care, and proactive interventions can significantly improve the safety, efficacy, and overall quality of life for patients undergoing chemotherapy.

Date :
  1. Date Completed 2020-12-11
  2. Date Revised 2020-12-14
Further Info :

Pubmed ID

33268682

DOI: Digital Object Identifier

10.1248/yakushi.20-00122

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Languages

Japanese

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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