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Buprenorphine-naloxone use in pregnancy: a systematic review and metaanalysis.

Author: JonesHendree, KaltenbachKarol, LinkHeather M, MillerLauren, SeligmanNeil

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

A systematic review and meta-analysis found that pregnant women taking buprenorphine-naloxone for opioid use disorder do not have significantly different pregnancy outcomes compared to those taking other forms of opioid agonist medication-assisted therapy. Of 1875 mother-baby dyads analyzed, there were no serious adverse maternal or neonatal outcomes associated with buprenorphine-naloxone. Women on buprenorphine-naloxone were less likely to have babies who needed treatment for neonatal abstinence syndrome.
Paper Details　
Original Abstract of the Article :
OBJECTIVE: The goal of this systematic review and metaanalysis is to compare pregnancy outcomes between pregnant women undergoing treatment for opioid use disorder with buprenorphine-naloxone and those undergoing treatment for opioid use disorder with other forms of medication-assisted treatment. S...See full text at original site
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引用元：
https://doi.org/10.1016/j.ajogmf.2020.100179

データ提供：米国国立医学図書館（NLM）

Buprenorphine-Naloxone: A Safe and Effective Option for Opioid Use Disorder During Pregnancy

Opioid use disorder (OUD) poses significant challenges during pregnancy, and this study investigates the safety and efficacy of [buprenorphine-naloxone] as a medication-assisted treatment (MAT) option. It's like a quest for a safe and effective path through a treacherous landscape, aiming to improve outcomes for both mothers and their babies.

Buprenorphine-Naloxone: A Guiding Hand Through Pregnancy

The study found that [buprenorphine-naloxone] is associated with [no serious adverse maternal or neonatal outcomes], suggesting its safety and effectiveness as an MAT option during pregnancy. It's like a trusted guide, leading pregnant women through the challenges of OUD while protecting the well-being of both mother and child. The study also found that buprenorphine-naloxone was associated with a lower likelihood of [neonatal abstinence syndrome (NAS)] compared to other MAT medications.

Navigating Opioid Use Disorder During Pregnancy: A Collaborative Approach

This study highlights the importance of [MAT] for managing OUD during pregnancy, offering a safe and effective way to support women and their babies. It's like a community effort, where healthcare professionals, families, and support systems work together to ensure the best possible outcomes for mothers and their children. This research encourages a collaborative approach to addressing the complex challenges of OUD during pregnancy, prioritizing the well-being of both mother and child.

Dr.Camel's Conclusion

This study is a testament to the power of research and innovation in improving outcomes for pregnant women with OUD. It's like a desert caravan journey, where the collective efforts of many help to ensure a safe and successful arrival at the destination. The research highlights the importance of continued efforts to develop safe and effective MAT options, offering hope and support to women facing this challenging journey.

Date :
  1. Date Completed 2021-06-24
  2. Date Revised 2021-06-24
Further Info :

Pubmed ID

33345863

DOI: Digital Object Identifier

10.1016/j.ajogmf.2020.100179

Related Literature

Article Analysis
・Effective treatment of opioid use
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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