Paper Details

  1. Home
  2. Paper Details

Quantitative assessment of postsurgical breakdown of the blood-aqueous barrier following administration of 0.5% ketorolac tromethamine solution. A double-masked, paired comparison with vehicle-placebo solution study.

Author: FlachA J, GrahamJ, KrugerL P, StegmanR C, TanenbaumL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Ketorolac tromethamine solution was found to be more effective than a vehicle placebo in reducing blood-aqueous barrier breakdown after cataract surgery, as measured by fluorophotometry. Ketorolac was well-tolerated and had no effect on intraocular pressure.
Paper Details　
Original Abstract of the Article :
Preoperative and serial postoperative anterior chamber fluorophotometry were performed after oral administration of fluorescein sodium in patients undergoing extracapsular cataract extraction and posterior chamber intraocular lens insertion. The administration of topical 0.5% ketorolac tromethamine ...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1001/archopht.1988.01060130370024

データ提供：米国国立医学図書館（NLM）

Ketorolac: A Shield Against Post-Cataract Inflammation

This study investigates the use of ketorolac tromethamine solution, a non-steroidal anti-inflammatory drug (NSAID), to reduce post-operative inflammation following cataract surgery. Imagine a desert oasis, where the air is filled with dust and debris, irritating the eyes. Ketorolac acts like a protective shield, guarding against inflammation and ensuring a smooth recovery from cataract surgery.

Ketorolac: A Protective Oasis

This study found that ketorolac tromethamine solution significantly reduced the breakdown of the blood-aqueous barrier and decreased post-operative inflammation in patients undergoing cataract surgery. It's like finding a calming oasis in the desert of post-operative recovery, protecting the eyes and promoting a smooth healing process.

A Safer Option for Cataract Surgery

This study highlights the potential benefits of using ketorolac tromethamine solution as a non-steroidal alternative to corticosteroids for managing post-operative inflammation after cataract surgery. It's like finding a more sustainable way to protect the eyes from the harsh environment of post-surgical recovery. This research suggests that ketorolac tromethamine solution could be a safe and effective option for patients undergoing cataract surgery.

Dr. Camel's Conclusion

This study demonstrates the effectiveness of ketorolac tromethamine solution in reducing post-operative inflammation after cataract surgery. It's like finding a new oasis in the desert of post-surgical recovery, offering a safe and effective way to protect the eyes and promote healing. This research suggests that ketorolac tromethamine solution could be a valuable tool for ophthalmologists, ensuring a smoother and more comfortable recovery for patients undergoing cataract surgery.

Date :
  1. Date Completed 1988-04-07
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

3345153

DOI: Digital Object Identifier

10.1001/archopht.1988.01060130370024

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.