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Neoadjuvant treatment with androgen receptor signaling inhibitors prior to radical prostatectomy: a systematic review.

Author: BrigantiAlberto, ClaessensFrank, ClinckaertAndries, De MeerleerGert, DevliesWout, DevosGaëtan, GraefenMarkus, JoniauSteven, SteuberThomas, Van PoppelHendrik, VansevenantBram, de la TailleAlexandre

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

We need better ways to treat men with prostate cancer (PCa) that's localized (not spread) but has a high risk of coming back. Drugs that block androgen receptors (ARSI) have helped people with advanced prostate cancer that has spread, so we hope they could be helpful in the early stages as well.
Paper Details　
Original Abstract of the Article :
There is an urgent need to develop novel treatment strategies in patients with unfavorable intermediate- and high-risk localized prostate cancer (PCa) to optimize the outcome of these patients. Androgen receptor signaling inhibitors (ARSI) have demonstrated a survival benefit in metastatic hormonese...See full text at original site
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引用元：
https://doi.org/10.1007/s00345-021-03611-x

データ提供：米国国立医学図書館（NLM）

Neoadjuvant Treatment for Prostate Cancer: A New Frontier

The landscape of [oncology] is continuously evolving, with new treatment strategies emerging to combat [prostate cancer]. This study delves into the potential of [neoadjuvant treatment] with [androgen receptor signaling inhibitors (ARSI)] prior to [radical prostatectomy] for patients with [unfavorable intermediate- and high-risk localized prostate cancer]. The authors systematically review the available evidence, exploring the potential benefits of this novel approach in improving outcomes for these challenging cases. This research sheds light on a promising new avenue for treating [prostate cancer], offering hope for a more effective and personalized approach to patient care.

The Promise of Personalized Treatment

The authors highlight the importance of personalized treatment strategies for [prostate cancer]. They underscore the potential of [neoadjuvant treatment] with [ARSI] to tailor treatment plans to individual patient needs, potentially improving outcomes and enhancing the quality of life. This research is like a compass, guiding clinicians towards more effective and personalized treatment options for their patients.

A New Horizon in Prostate Cancer Treatment

This study offers a glimpse into a new horizon in [prostate cancer] treatment. The authors' systematic review provides a strong foundation for exploring the potential of [neoadjuvant ARSI therapy] as a promising approach to improve outcomes for patients with [unfavorable intermediate- and high-risk localized prostate cancer]. This research is a reminder that we must continually seek innovation to advance our understanding and treatment of this devastating disease.

Dr.Camel's Conclusion

The authors' focus on [neoadjuvant ARSI therapy] highlights the importance of embracing new treatment approaches in the ongoing battle against [prostate cancer]. This systematic review provides a valuable roadmap for exploring this novel strategy and its potential to improve patient outcomes. As we continue to navigate the desert of [oncology], this research serves as a reminder to always seek innovative solutions and embrace personalized approaches to patient care.

Date :
  1. Date Completed 2022-02-10
  2. Date Revised 2022-02-10
Further Info :

Pubmed ID

33580296

DOI: Digital Object Identifier

10.1007/s00345-021-03611-x

Related Literature

Article Analysis
・Effective treatment of prostate cancer
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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