Are biologics combined with methotrexate better than biologics monotherapy in psoriasis and psoriatic arthritis: A meta-analysis of randomized controlled trials.

Author: LiuYang, LiuYi, XieYan

Paper Details 
Original Abstract of the Article :
To investigate if the combination of biologics with methotrexate (MTX) would have better performance than biological monotherapy in clinical efficiency and safety for the treatment of psoriasis and psoriatic arthritis (PsA), a systematic review of randomized controlled trials (RCTs) searched from th...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://doi.org/10.1111/dth.14926

データ提供:米国国立医学図書館(NLM)

Biologics and Methotrexate: A Winning Combination for Psoriasis and Psoriatic Arthritis?

[Psoriasis and psoriatic arthritis] are chronic inflammatory conditions that require [effective treatment] to manage their symptoms. This meta-analysis examines the [efficacy of combining biologics with methotrexate (MTX)] in treating these conditions. The study found that [the combination therapy demonstrated greater improvement in psoriasis] compared to biologics alone, without increasing the risk of adverse events.

A Promising Therapeutic Strategy

[The combination of biologics and MTX appears to be a promising therapeutic strategy] for psoriasis. While [the study did not find significant differences in PsA treatment efficacy], further research is warranted to [explore the potential benefits of this combination therapy] for PsA.

Managing Psoriasis and Psoriatic Arthritis

This research provides valuable insights into [the treatment of psoriasis and PsA]. [Choosing the right treatment approach] is crucial for [effectively managing these conditions] and improving the quality of life for patients. It's encouraging to see [the continued development of new and effective treatment options] for these challenging conditions.

Dr. Camel's Conclusion

The desert can be a harsh and unforgiving environment, but with the right tools and strategies, we can [thrive even in the face of adversity]. This research reminds us that [collaboration and innovation] are essential for [tackling complex health challenges]. The combination of biologics and MTX offers a [promising approach] for managing psoriasis and PsA, highlighting the [power of scientific inquiry] to find solutions to human health issues.

Date :
  1. Date Completed 2021-06-30
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

33655646

DOI: Digital Object Identifier

10.1111/dth.14926

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.