Paper Details 
Original Abstract of the Article :
<b><i>Background:</i></b> Vonoprazan is a potassium-competitive acid blocker increasingly used in Japan to prevent upper gastrointestinal bleeding in patients undergoing dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI). Cytochrome P450 (CYP) 3A4 is involved in the pri...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7939790/

データ提供:米国国立医学図書館(NLM)

Vonoprazan: A Gastric Protector with a Surprising Twist

Protecting the stomach from the damaging effects of medication is a crucial aspect of patient care. This study investigates the potential interaction between vonoprazan, a gastric acid blocker, and prasugrel, an antiplatelet medication. The researchers conducted a clinical trial to assess the impact of vonoprazan on the antiplatelet function of prasugrel in patients undergoing percutaneous coronary intervention (PCI). Their findings suggest that vonoprazan does not significantly affect the antiplatelet effect of prasugrel, a reassuring finding for patients undergoing PCI who require both medications.

A Safe Combination: Vonoprazan and Prasugrel

The study revealed that vonoprazan did not compromise the antiplatelet effect of prasugrel, demonstrating a safe and effective combination for patients undergoing PCI. This finding is important for ensuring optimal patient care and minimizing the risk of cardiovascular events.

Balancing Gastric Protection and Heart Health

This research highlights the importance of considering potential drug interactions when prescribing medications. The findings suggest that vonoprazan can be safely used alongside prasugrel, providing both gastric protection and antiplatelet effects. Remember, my dear friends, just like the desert sands, we must be mindful of the interactions between different elements, and this research offers valuable insight into the complex world of drug interactions.

Dr.Camel's Conclusion

This research explores the potential interaction between vonoprazan, a gastric acid blocker, and prasugrel, an antiplatelet medication. The findings suggest that these medications can be safely used in combination, providing both gastric protection and antiplatelet effects for patients undergoing percutaneous coronary intervention.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-03-12
Further Info :

Pubmed ID

33693287

DOI: Digital Object Identifier

PMC7939790

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Languages

English

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