Prevalence and predictors of laxatives use in clozapine-related constipation: an observational study.

Author: NagamineTakahiko, NakamuraMasaru

Paper Details 
Original Abstract of the Article :
Clozapine-induced constipation is a frequently overlooked side effect that can prove fatal. This study aimed to investigate the prevalence of constipation and the breakdown of laxatives, and to identify whether use of laxative may be predicted by demographics or baseline metabolic markers in 53 Japa...See full text at original site
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引用元:
https://pubmed.ncbi.nlm.nih.gov/33724255

データ提供:米国国立医学図書館(NLM)

Constipation: A Common Challenge in Clozapine Treatment

This research explores the prevalent issue of constipation associated with clozapine, a medication used to treat schizophrenia. The study highlights the significant impact of clozapine-induced constipation on patients, emphasizing the need for proactive strategies to manage this side effect. The study found that half of the patients required laxative treatment, suggesting the need for vigilant monitoring and prompt intervention to prevent severe complications associated with constipation. The study further identified factors that predict the use of laxatives, providing valuable insights for personalized management of constipation in clozapine-treated patients.

Navigating Constipation: A Common Roadblock

This study delves into the challenging journey of managing constipation, a frequent side effect of clozapine treatment. Imagine navigating a desert, where water is scarce and dehydration can lead to severe consequences. Similarly, constipation can have significant health implications for patients, particularly those taking clozapine. This study provides valuable insights into the prevalence and predictors of clozapine-related constipation, offering crucial information for developing effective management strategies.

Constipation Management: Prioritizing Patient Well-being

This research underscores the importance of proactively addressing constipation in patients taking clozapine. Constipation can be a debilitating side effect, affecting quality of life and overall well-being. This study provides valuable insights into the predictors of laxative use, enabling healthcare professionals to identify patients at risk and implement appropriate interventions to prevent and manage constipation effectively. Just as a desert traveler must carefully manage water intake, so too must healthcare professionals prioritize the management of constipation in patients taking clozapine.

Dr. Camel's Conclusion

This study highlights the significant prevalence of constipation in patients taking clozapine and underscores the need for proactive strategies to manage this side effect. The study's findings suggest that a careful assessment of individual risk factors can guide personalized interventions for constipation management, contributing to improved patient outcomes and quality of life for those taking clozapine.
Date :
  1. Date Completed 2021-12-23
  2. Date Revised 2021-12-23
Further Info :

Pubmed ID

33724255

DOI: Digital Object Identifier

00004850-202105000-00008

Related Literature

SNS
PICO Info
in preparation
Languages

English

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