Safety and immunogenicity of inactivated hepatitis-A vaccine developed by Human Biologicals Institute in two age groups of healthy subjects: A phase I open label study.

Author: BarsodeSupriya, DiwanArundhati, LingalaRajendra, PalkarSonali, RajashakarB C, SahooDevi Prasad, SandhyaG, SatishM, SusarlaSai Krishna, SvPardha Saradhi

Paper Details 
Original Abstract of the Article :
Hepatitis-A is an acute viral infection of the liver. Hepatitis-A virus has worldwide spread and is endemic in India. Though the disease is self-limiting in most cases, outbreaks are reported frequently from both developing and developed countries of the world. Severity and fatality occur more among...See full text at original site
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引用元:
https://doi.org/10.1016/j.vaccine.2021.03.012

データ提供:米国国立医学図書館(NLM)

Inactivated Hepatitis-A Vaccine: A Shield Against a Global Threat

Hepatitis-A is a serious public health concern, with widespread outbreaks reported worldwide. This study, like a camel navigating a desert landscape, explores the safety and immunogenicity of an inactivated hepatitis-A vaccine developed by the Human Biologicals Institute. The researchers, using a [phase I, single arm, open label, multicenter trial], assessed the vaccine's safety and efficacy in two different age groups. Their findings, like an oasis providing much-needed relief, demonstrated that the vaccine was well-tolerated and elicited a robust immune response in both age groups, highlighting its potential as a valuable tool for preventing hepatitis-A infection.

A Vital Tool for Prevention: The Role of Hepatitis-A Vaccination

This study's findings, like a protective shield in the desert, emphasize the importance of vaccination in preventing hepatitis-A infection. The vaccine's safety and efficacy offer a powerful weapon in combating this global health threat.

Protecting Communities: The Benefits of Vaccination

Vaccination is a crucial tool for protecting individuals and communities from infectious diseases. By increasing vaccination rates, we can create a barrier against the spread of diseases like hepatitis-A, safeguarding the health and well-being of populations.

Dr.Camel's Conclusion

This study, like a camel carrying precious cargo through the desert, highlights the importance of vaccination in safeguarding public health. The findings demonstrate the safety and immunogenicity of an inactivated hepatitis-A vaccine, offering a vital tool for preventing this potentially serious infection.

Date :
  1. Date Completed 2021-05-24
  2. Date Revised 2022-05-31
Further Info :

Pubmed ID

33741190

DOI: Digital Object Identifier

10.1016/j.vaccine.2021.03.012

Related Literature

SNS
PICO Info
in preparation
Languages

English

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