Role of suppression of endometriosis with progestins before IVF-ET: a non-inferiority randomized controlled trial.

Author: Abdel-RasheedMazen, AbdullahAmeer, HosniMahmoud, KhairyMohammed, KhalifaEissa, MohammadHashem

Paper Details 
Original Abstract of the Article :
BACKGROUND: Endometriosis affects the responsiveness to ovarian stimulation. This study aimed to assess the role of Dienogest pretreatment for endometriosis suppression as compared to Gonadotropin-releasing hormone agonist (GnRHa) in patients with endometriosis pursuing IVF treatment. METHODS: In t...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8011082/

データ提供:米国国立医学図書館(NLM)

Endometriosis and IVF: Finding the Right Path in the Desert of Infertility

Endometriosis can significantly impact a woman's ability to conceive. This randomized controlled trial compares the effectiveness of two different pretreatment regimens for endometriosis suppression in women undergoing in vitro fertilization (IVF), seeking to optimize treatment outcomes and improve chances of pregnancy.

Dienogest vs. GnRHa: A Comparison of Pretreatment Regimens

The study found that both Dienogest and Gonadotropin-releasing hormone agonist (GnRHa) were effective in preparing women with endometriosis for IVF, with no significant differences in ovarian stimulation, response parameters, or pregnancy outcomes. This is like finding two well-worn paths in the desert, both leading to the same destination. However, the study also found that Dienogest was associated with a lower cost of treatment, fewer side effects, and better quality of life for patients.

Choosing the Right Path for Endometriosis Patients

This research provides valuable insights for women with endometriosis seeking IVF treatment. It highlights the potential of Dienogest as a cost-effective and well-tolerated alternative to GnRHa for pretreatment. It's important to consider the individual needs and preferences of patients when choosing a treatment path, ensuring a comfortable and successful journey through the desert of infertility.

Dr. Camel's Conclusion

This research offers a valuable comparison of two different pretreatment options for women with endometriosis undergoing IVF. It highlights the importance of considering both clinical effectiveness and quality of life when making treatment decisions. We must continue to explore the desert of reproductive medicine, seeking new oases of knowledge that will improve the lives of those struggling with infertility.

Date :
  1. Date Completed 2021-05-21
  2. Date Revised 2021-05-21
Further Info :

Pubmed ID

33784989

DOI: Digital Object Identifier

PMC8011082

Related Literature

SNS
PICO Info
in preparation
Languages

English

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