Safety and efficacy of ubrogepant in participants with major cardiovascular risk factors in two single-attack phase 3 randomized trials: ACHIEVE I and II.

Author: BlumenfeldAndrew M, HutchinsonSusan, LiptonRichard B, LuKaifeng, SevertLawrence, SilbersteinStephen D, YuSung Yun

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To examine the safety and efficacy of ubrogepant for acute treatment of migraine across cardiovascular (CV) disease risk categories. METHODS: ACHIEVE I and II were multicenter, double-blind, single-attack, phase 3 trials in adults with migraine, with or without aura. Participants were ra...See full text at original site
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引用元:
https://doi.org/10.1177/03331024211000311

データ提供:米国国立医学図書館(NLM)

Ubrogepant: A Safe and Effective Treatment for Migraine Across Cardiovascular Risk Categories

The field of [Migraine Treatment] is constantly seeking effective and safe treatments for this debilitating condition. This research investigates the safety and efficacy of [Ubrogepant] for the acute treatment of [migraine] in individuals with varying levels of [cardiovascular (CV) risk factors]. The researchers conducted two [phase 3 randomized clinical trials] to assess the effects of Ubrogepant across different CV risk categories. Their findings suggest that [Ubrogepant demonstrated comparable safety and efficacy across all CV risk categories, including those with moderate-high risk]. This suggests that [Ubrogepant represents a safe and effective treatment option for migraine sufferers, regardless of their CV risk factors].

A Step Towards Personalized Migraine Treatment

This research provides a significant step towards personalized migraine treatment, demonstrating the safety and efficacy of Ubrogepant across a wide range of CV risk categories. The findings suggest that [Ubrogepant can be confidently considered for migraine treatment, regardless of individual CV risk factors].

Easing the Burden of Migraine

The desert of migraine pain can be a harsh and isolating place to navigate. This study provides a glimmer of hope, suggesting that [Ubrogepant can offer a safe and effective treatment option for migraine sufferers across a wide range of CV risk factors]. This advancement in migraine treatment has the potential to significantly improve the quality of life for those affected by this condition.

Dr. Camel's Conclusion

This study highlights the safety and efficacy of Ubrogepant for migraine treatment across different cardiovascular risk categories, offering a valuable tool for managing this debilitating condition and improving the lives of those affected.

Date :
  1. Date Completed 2021-12-09
  2. Date Revised 2021-12-14
Further Info :

Pubmed ID

33874756

DOI: Digital Object Identifier

10.1177/03331024211000311

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Article Analysis
SNS
PICO Info
in preparation
Languages

English

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