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Future prospects of ketoprofen in improving the safety of the gastric mucosa.

Author: KuczyńskaJoanna, Nieradko-IwanickaBarbara

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), is commonly used for its analgesic, anti-inflammatory, and antipyretic properties. However, its use is limited by various side effects. Researchers are actively working to develop modified versions of ketoprofen to improve its safety profile.
Paper Details　
Original Abstract of the Article :
Ketoprofen (K) was synthesized in 1968. K belongs to nonsteroidal anti-inflammatory drugs (NSAIDs) and has analgesic, anti-inflammatory and antipyretic properties. K is commonly used due to rapid absorption, simple metabolism, high antinociceptive activity and fast blood brain barrier crossing. Howe...See full text at original site
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引用元：
https://doi.org/10.1016/j.biopha.2021.111608

データ提供：米国国立医学図書館（NLM）

Ketoprofen: A Promising NSAID with a Twist

Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to relieve pain and inflammation. This research focuses on ketoprofen (K), a popular NSAID, and explores its potential for improving the safety of gastric mucosa, a common concern associated with NSAID use.

Balancing Pain Relief and Gastric Protection

The study highlights the need for safer NSAIDs that can effectively manage pain and inflammation without causing significant damage to the gastric mucosa. By modifying ketoprofen's structure, researchers aim to develop an improved version that retains its therapeutic benefits while minimizing its gastrointestinal side effects. This research represents a quest for a more balanced approach to NSAID therapy, ensuring both pain relief and gastric protection.

A Safer Future for NSAID Use

This research offers a promising path towards safer NSAID use. By understanding the mechanisms underlying ketoprofen's gastrointestinal side effects, researchers can develop modified versions of this drug that are more effective and less harmful to the stomach. This research is like finding a hidden spring in a desert, offering a potential solution for a common challenge associated with NSAID use.

Dr.Camel's Conclusion

NSAIDs are like a desert oasis, offering relief from pain and inflammation. But like some oases, they can also harbor hidden dangers. This research on ketoprofen is like discovering a new wellspring of knowledge, paving the way for safer and more effective NSAIDs. By understanding the nuances of ketoprofen's effects, we can create a more sustainable oasis for patients in need of pain relief.

Date :
  1. Date Completed 2021-08-11
  2. Date Revised 2021-08-11
Further Info :

Pubmed ID

33932737

DOI: Digital Object Identifier

10.1016/j.biopha.2021.111608

SNS
PICO Info
in preparation
Languages

English

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