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Effects of Analgesics on Tumor Growth in Mouse Models of Prostate Cancer Bone Metastasis.

Author: Daignault-NewtonStephanie, Escara-WilkeJune F, KellerEvan T, KellerJill M, MartinTara L, RobinsonTyler J, ThurstonSarah E, XuJiajie J

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examined the effects of two commonly used analgesics, carprofen and buprenorphine, on tumor growth in two mouse models of prostate cancer bone metastasis. The results suggest that a single injection of either analgesic at the time of tumor implantation did not significantly impact tumor growth or animal welfare, supporting the use of analgesia in such studies.
Paper Details　
Original Abstract of the Article :
Murine models of tumor development often require invasive procedures for tumor implantation, potentially causing pain or distress. However, analgesics are often withheld during implantation because of concerns that they may adversely affect tumor development. Previous studies examining the effects o...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8145123/

データ提供：米国国立医学図書館（NLM）

Pain Relief and Prostate Cancer Bone Metastasis: Finding a Balance

Prostate cancer, a challenging disease that affects millions worldwide, can spread to the bones, causing significant pain and discomfort. This study explores the potential impact of analgesics on tumor growth in mouse models of prostate cancer bone metastasis. This is like navigating a treacherous desert landscape, seeking to find a balance between alleviating pain and preventing disease progression.

Alleviating Pain Without Compromising Treatment

The study found that administering analgesics (carprofen or buprenorphine) at the time of tumor cell injection did not significantly impact tumor growth. This is like discovering a hidden oasis in a desert landscape, providing relief from pain without hindering the effectiveness of the treatment journey. This research provides valuable insights into the potential compatibility of pain relief with cancer treatment, offering hope for improved patient well-being.

Navigating the Desert of Cancer Treatment

This study highlights the importance of considering both pain management and disease progression when treating cancer. The findings suggest that analgesics can be safely administered without compromising treatment effectiveness. This is like finding a safe passage through a potentially dangerous desert, ensuring the comfort and well-being of the traveler while maintaining the journey toward a positive outcome.

Dr. Camel's Conclusion

This research offers promising findings for individuals with prostate cancer bone metastasis, suggesting that analgesics can be safely administered without compromising the efficacy of treatment. Finding a balance between pain relief and disease management is crucial for ensuring the well-being of cancer patients. Just as a skilled desert guide navigates the treacherous landscape, a compassionate healthcare team can help guide patients through the challenges of cancer treatment, ensuring both comfort and effective care.

Date :
  1. Date Completed 2021-09-22
  2. Date Revised 2021-11-02
Further Info :

Pubmed ID

33952382

DOI: Digital Object Identifier

PMC8145123

Related Literature

Article Analysis
・Effects of buprenorphine injection (pain relief)
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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