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Efficacy and safety of jakinibs in rheumatoid arthritis: a systematic review and meta-analysis.

Author: ChangXin, HeMichun, LiuMengru, WangMingjun, WuJian, YinYufeng, ZhouErye

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This systematic review found that jakinibs are effective and well tolerated in patients with rheumatoid arthritis (RA) up to 24 weeks. Jakinibs increased the clinical response rate at 12 and 24 weeks, but also increased the risk of infections.
Paper Details　
Original Abstract of the Article :
OBJECTIVES: To assess the efficacy and safety of jakinibs for the treatment of active rheumatoid arthritis (RA) in patients with an inadequate response or intolerance to conventional synthetic or biologic disease-modifying antirheumatic drugs (DMARDs). METHODS: A systematic search was conducted in ...See full text at original site
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引用元：
https://doi.org/10.1007/s10067-021-05686-8

データ提供：米国国立医学図書館（NLM）

Efficacy and safety of jakinibs in rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic inflammatory disease that affects the joints. Jakinibs are a new class of medications used to treat RA. This study aimed to evaluate the efficacy and safety of jakinibs in patients with RA who had an inadequate response or intolerance to conventional treatments.

Jakinibs: A Promising Treatment for Rheumatoid Arthritis

The study, a systematic review and meta-analysis of 28 randomized controlled trials, found that jakinibs were effective in improving RA symptoms and were well-tolerated. The study also found that jakinibs were associated with an increased risk of infections. These findings suggest that jakinibs might be a valuable treatment option for RA, but careful monitoring for infections is crucial.

Navigating the Labyrinth of Rheumatoid Arthritis

RA, like a labyrinthine desert, can be a challenging condition to manage. This study offers valuable insights into the potential of jakinibs as a treatment option for RA. While these medications show promise, it's essential to understand their potential side effects, particularly the increased risk of infections, and manage them effectively.

Dr.Camel's Conclusion

This study explores the potential of jakinibs as a new weapon in the fight against rheumatoid arthritis. Just as a camel navigates the harsh desert landscape, individuals with RA often face significant challenges. Jakinibs might offer a path to improved function and quality of life, but it's essential to stay vigilant and address any potential risks.

Date :
  1. Date Completed 2021-09-28
  2. Date Revised 2021-09-28
Further Info :

Pubmed ID

33990888

DOI: Digital Object Identifier

10.1007/s10067-021-05686-8

Related Literature

Article Analysis
・Effective treatment of rheumatoid arthritis
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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