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Safety and discontinuation rate of immune checkpoint inhibitors used in patients with solid and hematological malignancies. A population based retrospective analysis.
Author: AlfayeaTurki, AlnatshehAbdelmajid, AlshamraniMajed, AseeriMohammed, ShahbarAlaa
Original Abstract of the Article :
The discovery of immune checkpoint inhibitors caused a paradigm shift in cancer treatment and led to a major improvement in clinical outcomes. However, they may induce inflammatory side effects that are known as immune-related adverse effect (iRAE). This study aimed to assess the safety profile and ...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/10781552211017634
データ提供:米国国立医学図書館(NLM)
Safety and Discontinuation Rate of Immune Checkpoint Inhibitors Used in Patients with Solid and Hematological Malignancies: A Population-Based Retrospective Analysis
Immune checkpoint inhibitors (ICIs), a revolutionary advancement in cancer treatment, have transformed the landscape of cancer care. These powerful drugs, like a skilled army of immune cells trained to attack cancer, can unleash the body’s own defenses against disease. However, like any powerful weapon, ICIs can have side effects, and it’s essential to understand their safety profile. This study, like a cautious military strategist assessing the risks and benefits of a new weapon, conducted a retrospective analysis of ICI safety and discontinuation rates in patients with various types of cancer.
Navigating the Side Effects of a Powerful Weapon
The study, like a detailed battlefield report, revealed that ICIs can induce a variety of immune-related adverse events (iRAEs), but these side effects are often manageable with appropriate treatment. While iRAEs are a concern, they do not necessarily preclude the use of ICIs, and the benefits of these therapies often outweigh the risks for many patients. The study also highlighted the importance of careful monitoring for iRAEs and prompt intervention when necessary.
Managing the Side Effects of Cancer Treatment
Cancer treatment, like a long and challenging desert journey, can come with its own set of challenges and side effects. It’s important to work closely with your healthcare team to manage any side effects and ensure that you receive the best possible care. Don’t hesitate to communicate any concerns or questions you may have about your treatment, as open communication is key to managing the side effects of cancer therapy.
Dr.Camel's Conclusion
This study, like a well-equipped caravan venturing into a vast desert, provides valuable information about the safety and effectiveness of immune checkpoint inhibitors. It highlights the importance of carefully assessing the risks and benefits of these powerful therapies and emphasizes the need for vigilant monitoring and prompt intervention when necessary.
Date :
- Date Completed 2022-04-29
- Date Revised 2022-04-29
Further Info :
Related Literature
English
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