Paper Details 
Original Abstract of the Article :
The aims of this study were: (1) to perform population pharmacokinetic analysis of cefaclor in healthy Korean subjects, and (2) to investigate possible effects of various covariates on pharmacokinetic parameters of cefaclor. Although cefaclor belongs to the cephalosporin family antibiotic that has b...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160640/

データ提供:米国国立医学図書館(NLM)

Population Pharmacokinetic Analysis of Cefaclor in Healthy Korean Subjects

The field of [Pharmacokinetics] is crucial for understanding how [Drugs] are absorbed, distributed, metabolized, and eliminated from the body. This research focuses on [Cefaclor], a commonly used [Antibiotic], and its pharmacokinetic behavior in [Healthy Korean subjects]. The researchers conducted a [Population pharmacokinetic analysis] to explore the variability in [Cefaclor pharmacokinetics] among individuals and identify factors that might influence [Drug levels]. The findings offer valuable insights into [Optimizing cefaclor dosing] for this specific population.

Factors Influencing Cefaclor Pharmacokinetics

The study reveals that [Creatinine clearance and body weight] significantly influence [Cefaclor's systemic clearance and distribution volume]. This finding emphasizes the need for [Personalized dosing] based on individual patient characteristics, ensuring that [Appropriate drug levels] are achieved for optimal therapeutic efficacy. The research underscores the importance of considering [Individual variability] in drug metabolism when prescribing medications.

Navigating the Complexities of Drug Metabolism

This research provides valuable information for [Healthcare professionals] prescribing [Cefaclor] in [Korean patients]. It highlights the importance of [Tailoring dosing regimens] to individual characteristics to ensure optimal therapeutic outcomes. The study emphasizes the need for [Continued research] to further understand [Drug pharmacokinetics] in diverse populations and refine [Dosing recommendations] for various medications.

Dr. Camel's Conclusion

Just as a camel adapts its journey through the desert based on the terrain and available resources, [Healthcare professionals] must adapt [Medication regimens] to the unique characteristics of each patient. This research provides valuable insights into [Cefaclor pharmacokinetics] in [Korean subjects], emphasizing the need for [Personalized medicine] to ensure the best possible outcomes for patients.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-06-15
Further Info :

Pubmed ID

34069627

DOI: Digital Object Identifier

PMC8160640

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Languages

English

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