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[Double-blind trial of 2 antidepressive drugs].

Author: De LeónO, KravcioJ T, SánchezC

English AbstractA summary of a research paper/publication written in English for a wider audience.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Viloxazine was found to be as effective as Desipramine in treating hospitalized depressives. Both drugs significantly reduced symptoms after one week of treatment. The main side effects of Viloxazine were nausea and dizziness, while Desipramine caused the usual antidepressant side effects.
Paper Details　
Original Abstract of the Article :
The results of a double blind trial of Viloxazine and Desipramine in 30 hospitalized depressives are reported. Hamilton's Rating Scale for Depression was the outcome criterion. No statistically significant differences were found between drugs in efficacy and onset of action. Patients on either drug ...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/341650

データ提供：米国国立医学図書館（NLM）

Exploring the Efficacy and Safety of Antidepressants: A Double-Blind Trial

This research embarks on a journey into the world of depression treatment, comparing the effectiveness of two antidepressants, viloxazine and desipramine, in a double-blind trial. It's like navigating a vast desert, where each medication is a different path, leading to varying outcomes for those seeking relief. The researchers used Hamilton's Rating Scale for Depression to evaluate the efficacy of each medication and documented the observed side effects. This study provides valuable insights into the comparative effectiveness of these antidepressants and highlights the importance of individual responses to treatment.

Viloxazine: A Promising Alternative in Antidepressant Treatment

The study found that viloxazine demonstrated similar efficacy to desipramine in reducing depression symptoms. This finding suggests that viloxazine may be a viable alternative for treating depression, especially for patients who may not tolerate desipramine's side effects. It's like discovering a hidden oasis in the desert of antidepressant treatment, offering a refreshing alternative for those seeking relief. The study also emphasized the need for careful monitoring of side effects, especially in patients with cardiovascular issues or those taking medications that could interact with antidepressants.

Navigating the Desert of Depression Treatment: Choosing the Right Path

This research underscores the importance of individualizing treatment approaches for depression. It's like navigating a vast desert, where the path that leads to relief may differ for each traveler. This study encourages healthcare professionals to consider the potential benefits and side effects of various antidepressants, ensuring that patients receive the most appropriate and effective treatment for their unique needs.

Dr.Camel's Conclusion

This study sheds light on the complexities of depression treatment, highlighting the need for a personalized approach. It underscores the importance of considering individual responses to medication and carefully monitoring for side effects. As we continue to navigate the vast desert of mental health research, studies like this provide valuable insights into the most effective and safe treatment strategies for depression.

Date :
  1. Date Completed 1978-03-21
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

341650

DOI: Digital Object Identifier

341650

Related Literature

Article Analysis
・Side Effects of viloxazine
SNS
PICO Info
in preparation
Languages

Spanish

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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