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New Pharmacological Targets for the Treatment of Schizophrenia: A Literature Review.

Author: BellomoAntonello, BorraccinoLuisa, CuocoFederica, De BerardisDomenico, Delle MonacheSonia, FornaroMichele, GianfeliceGiulia, MagnificoGiuseppe, PiccininniCarla, RicciFabiana, RinaldiAngelo, VentriglioAntonio

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Schizophrenia is treated with antipsychotic medications that block dopamine and serotonin. However, 20-40% of people with schizophrenia don't respond well to these medications or continue to have symptoms. We need new ways to treat schizophrenia that can improve their thinking skills and daily functioning.
Paper Details　
Original Abstract of the Article :
The pharmacological treatment of schizophrenia is currently based on the employment of antipsychotic medications showing an antagonism of dopaminergic and serotoninergic inhibitors. 20-40% of patients are drug-resistant or residually symptomatic in the long-term antipsychotic treatment, and new stra...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.2174/1568026621666210701103147

データ提供：米国国立医学図書館（NLM）

New Pharmacological Targets for Schizophrenia: A Literature Review

Schizophrenia is a complex mental illness that poses significant challenges for both patients and clinicians. This research explores the current pharmacological treatment landscape for schizophrenia and identifies potential new targets for therapeutic interventions. The study reviews the limitations of existing antipsychotic medications, highlighting the need for novel approaches to address the unmet needs of patients with schizophrenia. The research explores promising new targets, focusing on the potential for improving functional and cognitive impairment in patients with schizophrenia.

Expanding the Horizons of Schizophrenia Treatment

The study's findings highlight the need for innovative approaches to treating schizophrenia. The limitations of current antipsychotic medications emphasize the importance of research focused on identifying new pharmacological targets and developing more effective therapies. This research underscores the ongoing pursuit of better treatment options for patients with schizophrenia.

Improving the Lives of Individuals with Schizophrenia

The study's focus on new pharmacological targets emphasizes the importance of research dedicated to improving the lives of individuals with schizophrenia. By identifying new treatment options and exploring potential therapies that address the unmet needs of patients, research plays a crucial role in advancing the understanding and management of schizophrenia.

Dr. Camel's Conclusion

Just as a camel navigates the vast and often unpredictable desert, researchers are constantly seeking new pathways to navigate the complexities of schizophrenia. This review provides a valuable overview of the current treatment landscape and identifies potential new targets for therapeutic interventions, offering hope for those seeking more effective treatments for this challenging condition.

Date :
  1. Date Completed 2022-02-08
  2. Date Revised 2022-02-08
Further Info :

Pubmed ID

34218785

DOI: Digital Object Identifier

10.2174/1568026621666210701103147

Related Literature

Article Analysis
・Effective treatment of schizophrenia
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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