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Original Abstract of the Article :
BACKGROUND: Naratriptan, marketed in a low oral dose of 2.5 mg, is generally regarded as a less-effective triptan with a slower onset of action than most other triptans in the treatment of migraine attacks. In this review, naratriptan will be compared with sumatriptan, the standard triptan. METHODS...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1177/03331024211028959
データ提供:米国国立医学図書館(NLM)
Naratriptan's Effectiveness for Migraine: A Re-evaluation of a Gentle Triptan
In the field of [migraine treatment], finding the right medication can be a bit like searching for an oasis in the desert. This mini-review examines the effectiveness of naratriptan, a triptan often considered less potent than others, by comparing it to sumatriptan, the standard triptan. The authors analyzed data from both animal models and human clinical trials.
Naratriptan's Effectiveness Depends on the Dose
The research highlights the importance of dose-response relationship when considering the effectiveness of naratriptan. While a lower dose (2.5 mg) of naratriptan was less effective than sumatriptan 100 mg, a higher dose (10 mg) demonstrated similar effectiveness. Interestingly, subcutaneous naratriptan 10 mg was superior to subcutaneous sumatriptan 6 mg in one trial, suggesting that the route of administration might also play a role.
Finding the Right Triptan for Migraine Relief
The choice of migraine medication depends on individual needs and preferences. This review emphasizes the importance of considering both dose and administration route when selecting a triptan. It's crucial to consult with a physician to find the best treatment option for your specific needs.
Dr. Camel's Conclusion
This mini-review reveals that naratriptan, when used at an appropriate dose, can be as effective as sumatriptan in treating migraine attacks. This finding is significant because it expands the options available to patients seeking relief from migraine pain. Remember, just as a camel adapts to the harsh conditions of the desert, we need to find the right medication to adapt to our individual needs.
Date :
- Date Completed 2022-01-17
- Date Revised 2022-01-17
Further Info :
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