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Drug-induced Urinary Retention: An Analysis of a National Spontaneous Adverse Drug Reaction Reporting Database.

Author: CrisafulliSalvatore, CutroneoPaola Maria, Di GiovanniValentina, FerrajoloCarmen, FicarraVincenzo, SottosantiLaura, SpinaEdoardo, TrifiròGianluca, VerhammeKatia

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Five drugs, dapagliflozin, gabapentin, lithium, celecoxib, and piroxicam, were identified as potential new signals for urinary retention (UR), requiring further evaluation.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Numerous drugs have been associated with urinary retention (UR), but updated information on drugs that may induce UR is limited. OBJECTIVE: To evaluate drug-induced UR using the Italian spontaneous adverse drug reactions (ADRs) reporting database. DESIGN, SETTING, AND PARTICIPANTS: We ...See full text at original site
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引用元：
https://doi.org/10.1016/j.euf.2021.07.001

データ提供：米国国立医学図書館（NLM）

Drug-Induced Urinary Retention: An Analysis of a National Spontaneous Adverse Drug Reaction Reporting Database

Urinary retention (UR) is a common side effect of certain medications. This study analyzed the Italian spontaneous adverse drug reactions (ADRs) reporting database to identify drugs potentially associated with UR and assess the characteristics of patients experiencing this side effect.

Identifying Potential New UR Signals

The analysis identified five drugs—dapagliflozin, gabapentin, lithium, celecoxib, and piroxicam—as potential new signals for UR. These findings highlight the need for further investigation to confirm these associations and understand the mechanisms by which these drugs may contribute to UR.

Promoting Safer Medication Use

This study underscores the importance of continuously monitoring and analyzing ADR reports to identify potential drug-related side effects. By identifying new signals for UR, healthcare professionals can make more informed decisions about medication choices and minimize the risk of this potentially debilitating side effect.

Dr.Camel's Conclusion

This study highlights the importance of monitoring and analyzing spontaneous ADR reports for identifying potential drug-related side effects. The analysis of the Italian ADR database revealed potential new signals for UR, prompting further investigation and contributing to safer medication practices.

Date :
  1. Date Completed 2022-12-05
  2. Date Revised 2022-12-14
Further Info :

Pubmed ID

34275763

DOI: Digital Object Identifier

10.1016/j.euf.2021.07.001

SNS
PICO Info
in preparation
Languages

English

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