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Renal adverse drug reactions.

Author: HughesChristine

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.

Overview

This review discusses the prevalence of chronic kidney disease (CKD) in people living with HIV (PLWH). Advancing age, cardiometabolic risk factors, and antiretroviral drugs can contribute to CKD in this population. Switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) in people with baseline renal dysfunction improves renal parameters. More research is needed on the long-term safety and benefit of TAF in individuals at low risk of CKD.
Paper Details　
Original Abstract of the Article :
PURPOSE OF REVIEW: Chronic kidney disease (CKD) is common in people living with HIV (PLWH) and is related to a multitude of factors. The aim of this review is to provide an overview of the most recent evidence of renal adverse effects of antiretroviral drugs, predictors of CKD risk and areas for fut...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/34459469

データ提供：米国国立医学図書館（NLM）

Renal Adverse Drug Reactions in People with HIV

Chronic kidney disease (CKD) is a growing concern for people living with HIV (PLWH). This study reviews the latest evidence on renal adverse effects associated with antiretroviral drugs, exploring the risk factors for CKD in this population. The researchers highlight the importance of selecting appropriate antiretroviral therapy (ART) to minimize renal toxicity.

Navigating the Desert of Antiretroviral Therapy

This study sheds light on the complex relationship between antiretroviral therapy and renal health in people living with HIV. The researchers emphasize the need for careful consideration of potential renal adverse effects and the importance of selecting ART regimens that minimize risk. It's like navigating a desert with various paths, choosing the route that minimizes the risk of encountering treacherous terrain.

Ensuring Optimal Renal Health for People with HIV

This review underscores the importance of monitoring renal function in PLWH and making informed decisions regarding ART to mitigate CKD risk. By understanding the potential renal adverse effects of antiretroviral drugs and the factors contributing to CKD development, healthcare providers can optimize treatment strategies to ensure long-term health and well-being for individuals with HIV.

Dr.Camel's Conclusion

This review highlights the importance of managing renal health in people living with HIV, emphasizing the need for careful consideration of antiretroviral drug selection and ongoing monitoring. It's crucial to strike a balance between controlling HIV infection and minimizing the risk of kidney damage. By carefully navigating the desert of antiretroviral therapy, we can optimize treatment strategies and ensure a healthier future for individuals with HIV.

Date :
  1. Date Completed 2021-10-22
  2. Date Revised 2023-09-03
Further Info :

Pubmed ID

34459469

DOI: Digital Object Identifier

01222929-202111000-00005

SNS
PICO Info
in preparation
Languages

English

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