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Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair.
Author: EliseevRoman A, HollenbergAlex M, HuberAric, SmithCharles O
Original Abstract of the Article :
Bone fracture is a growing public health burden and there is a clinical need for non-invasive therapies to aid in the fracture healing process. Previous studies have demonstrated the utility of electromagnetic (EM) fields in promoting bone repair; however, its underlying mechanism of action is uncle...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476611/
データ提供:米国国立医学図書館(NLM)
Harnessing Electromagnetic Stimulation for Bone Fracture Repair
Bone fracture is a common injury, causing significant pain and disruption to daily life. This study, published in [論文が掲載された雑誌名], investigates the potential of electromagnetic (EM) field therapy as a non-invasive treatment for bone fracture repair. Researchers explored the mechanism by which EM fields stimulate the healing process, focusing on their impact on mitochondria, the energy powerhouses of our cells.
EM Fields and Mitochondrial Activity
The study found that applying a low-intensity constant EM field to osteogenic cells in vitro stimulated mitochondrial function, leading to increased mitochondrial membrane potential and respiratory complex I activity. This increased mitochondrial activity, in turn, promoted the differentiation of osteoprogenitor cells into osteoblasts, the bone-forming cells. Importantly, the researchers also showed that the osteoinductive effect was reversed in the presence of antimycin A, a mitochondrial inhibitor, confirming the role of mitochondrial activity in the bone healing process. Further, they demonstrated that EM field therapy also enhanced fracture repair in a mouse model, improving biomechanical properties and increasing callus bone mineralization.
A New Frontier in Bone Healing
This research opens exciting possibilities for EM field therapy as a non-invasive treatment for bone fracture repair. It's like harnessing the power of a desert wind to accelerate the healing process. By stimulating mitochondrial function, EM fields may provide a natural and effective way to promote bone healing, offering a promising alternative to traditional treatments.
Dr. Camel's Conclusion
This study unveils the potential of EM field therapy as a promising new approach to bone fracture repair. Like a desert oasis providing life-giving water, EM fields can energize the healing process, offering hope for a faster and more effective recovery. Further research in this area will continue to refine our understanding of how to harness the power of EM fields for promoting bone healing.
Date :
- Date Completed 2021-12-28
- Date Revised 2021-12-28
Further Info :
Related Literature
English
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