Electromagnetic stimulation increases mitochondrial function in osteogenic cells and promotes bone fracture repair.

Author: EliseevRoman A, HollenbergAlex M, HuberAric, SmithCharles O

Paper Details 
Original Abstract of the Article :
Bone fracture is a growing public health burden and there is a clinical need for non-invasive therapies to aid in the fracture healing process. Previous studies have demonstrated the utility of electromagnetic (EM) fields in promoting bone repair; however, its underlying mechanism of action is uncle...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8476611/

データ提供:米国国立医学図書館(NLM)

Harnessing Electromagnetic Stimulation for Bone Fracture Repair

Bone fracture is a common injury, causing significant pain and disruption to daily life. This study, published in [論文が掲載された雑誌名], investigates the potential of electromagnetic (EM) field therapy as a non-invasive treatment for bone fracture repair. Researchers explored the mechanism by which EM fields stimulate the healing process, focusing on their impact on mitochondria, the energy powerhouses of our cells.

EM Fields and Mitochondrial Activity

The study found that applying a low-intensity constant EM field to osteogenic cells in vitro stimulated mitochondrial function, leading to increased mitochondrial membrane potential and respiratory complex I activity. This increased mitochondrial activity, in turn, promoted the differentiation of osteoprogenitor cells into osteoblasts, the bone-forming cells. Importantly, the researchers also showed that the osteoinductive effect was reversed in the presence of antimycin A, a mitochondrial inhibitor, confirming the role of mitochondrial activity in the bone healing process. Further, they demonstrated that EM field therapy also enhanced fracture repair in a mouse model, improving biomechanical properties and increasing callus bone mineralization.

A New Frontier in Bone Healing

This research opens exciting possibilities for EM field therapy as a non-invasive treatment for bone fracture repair. It's like harnessing the power of a desert wind to accelerate the healing process. By stimulating mitochondrial function, EM fields may provide a natural and effective way to promote bone healing, offering a promising alternative to traditional treatments.

Dr. Camel's Conclusion

This study unveils the potential of EM field therapy as a promising new approach to bone fracture repair. Like a desert oasis providing life-giving water, EM fields can energize the healing process, offering hope for a faster and more effective recovery. Further research in this area will continue to refine our understanding of how to harness the power of EM fields for promoting bone healing.

Date :
  1. Date Completed 2021-12-28
  2. Date Revised 2021-12-28
Further Info :

Pubmed ID

34580378

DOI: Digital Object Identifier

PMC8476611

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.