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Pneumatosis intestinalis and spontaneous perforation associated with drug toxicity in oncologic patients: a case series.

Author: ArdizzoniA, BalacchiC, BrandiN, BrocchiS, Dall'OlioF G, GaudianoC, GolfieriR, ParmeggianiA, RenzulliM, RihawiK

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Pneumatosis Intestinalis (PI), a rare radiological finding, can occur as an adverse effect of anti-tumor drugs. This study retrospectively analyzed 8 cases of PI detected in oncologic patients receiving various therapeutic regimens. Three patients were asymptomatic and treated conservatively, while five patients presented acute abdomen symptoms leading to bowel perforation and death.
Paper Details　
Original Abstract of the Article :
Pneumatosis Intestinalis (PI) is a rare radiological finding defined as the presence of extra-luminal gas within the intestinal wall. Several anti-tumor drugs can induce a damage of the gastrointestinal walls as an adverse effect, causing loss of mucosal integrity and endoluminal gas diffusion, resp...See full text at original site
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引用元：
https://doi.org/10.51821/84.3.015

データ提供：米国国立医学図書館（NLM）

Pneumatosis Intestinalis: A Rare Desert Oasis in Oncologic Patients

Pneumatosis intestinalis (PI) is a rare condition characterized by the presence of air in the intestinal wall. This research investigates the occurrence of PI and spontaneous perforation in oncologic patients undergoing various treatment regimens. The authors analyze a case series of patients who developed PI as an adverse effect of anti-tumor drugs, highlighting the importance of recognizing this potential complication in patients receiving cancer therapy.

Drug Toxicity: A Potential Desert Storm in Oncologic Patients

This study underscores the importance of carefully monitoring oncologic patients for potential adverse effects of anti-tumor drugs, particularly those that can affect the gastrointestinal tract. The authors highlight the risk of PI and spontaneous perforation as rare but potentially serious complications of drug toxicity.

Navigating the Desert of Cancer Treatment: A Vigilant Approach

This research reminds us that the desert of cancer treatment can be fraught with potential challenges. The authors emphasize the importance of vigilance in monitoring patients for adverse effects, particularly those related to drug toxicity, to ensure optimal patient safety and outcomes.

Dr.Camel's Conclusion

This study sheds light on the rare but potentially serious complication of pneumatosis intestinalis in oncologic patients. The authors highlight the importance of being aware of this adverse effect and carefully monitoring patients receiving anti-tumor drugs, particularly those that can affect the gastrointestinal tract.

Date :
  1. Date Completed 2021-10-05
  2. Date Revised 2021-10-05
Further Info :

Pubmed ID

34599575

DOI: Digital Object Identifier

10.51821/84.3.015

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Languages

English

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