Paper Details 
Original Abstract of the Article :
Aromatase inhibitors (AIs), such as anastrozole, letrozole, and exemestane, are commonly used as adjuvant endocrine therapy in hormone-receptive breast cancer in postmenopausal women. Their adverse effects are well documented, except for visual disturbances. The purpose of this study was to review t...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8482805/

データ提供:米国国立医学図書館(NLM)

Aromatase Inhibitors: A Look at Potential Ocular Side Effects

Aromatase inhibitors (AIs), such as anastrozole, letrozole, and exemestane, are commonly used in the treatment of breast cancer. While AIs have been well-studied for their systemic side effects, their potential impact on eye health has received less attention. This review examines the current literature on ocular complications associated with AI use. The study identifies several rare cases of ocular side effects, including papilloedema, macular oedema, uveitis, and retinopathy, associated with anastrozole and letrozole. The authors also note the potential for AI use to lead to ocular surface diseases such as corneal epithelial changes, blepharitis, and keratitis. The study emphasizes the need for heightened clinical suspicion when assessing patients with visual symptoms who are on AIs and calls for larger prospective studies to further investigate these potential complications.

Navigating the Desert of Potential Side Effects

This review highlights the importance of considering potential ocular side effects when using aromatase inhibitors for breast cancer treatment. While these side effects may be rare, the study emphasizes the need for vigilance and careful monitoring of patients on AIs. This is like navigating a desert landscape, where unexpected obstacles and challenges can arise. Clinicians must be prepared to recognize and address any potential side effects, ensuring patient safety and well-being.

Protecting Our Vision: A Multifaceted Approach

This research emphasizes the importance of a multifaceted approach to patient care, considering not only the primary treatment goals but also potential side effects that can impact overall health and well-being. This study serves as a reminder to be vigilant about potential ocular complications associated with aromatase inhibitors, ensuring that patients receive comprehensive and personalized care. This research is like navigating a vast desert landscape, where a multidisciplinary team of experts works together to ensure the safety and well-being of the travelers, guiding them toward a healthy destination.

Dr. Camel's Conclusion

This review highlights the potential for ocular complications associated with aromatase inhibitor use, emphasizing the need for heightened clinical suspicion and further research to better understand and manage these side effects.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-10-15
Further Info :

Pubmed ID

34646621

DOI: Digital Object Identifier

PMC8482805

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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