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Amantadine Revisited: A Contender for Initial Treatment in Parkinson's Disease?
Author: FeldmanMatthew, MargoleskyJason, MarmolSarah, SingerCarlos
Original Abstract of the Article :
The best practice for the initiation of symptomatic motor treatment for Parkinson's disease is an ongoing topic of debate. Fueled by interpretation of the results of the LEAP and MED Parkinson's disease studies, many practitioners opt for early initiation of levodopa formulations, avoiding dopamine ...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s40263-021-00862-5
データ提供:米国国立医学図書館(NLM)
Amantadine: A Potential Contender for Parkinson's Disease Treatment
The treatment of Parkinson's disease, a neurodegenerative disorder, is a complex and constantly evolving field. This article examines the potential of amantadine as an initial treatment option for Parkinson's disease, contrasting it with the commonly used levodopa and dopamine agonists. The author argues that amantadine, while currently mainly used as an add-on therapy, could be a valuable initial treatment option due to its effectiveness, safety profile, and lack of association with impulse control disorder.
Reappraising Amantadine's Role in Parkinson's Disease
This article advocates for a reevaluation of amantadine's role in the treatment of Parkinson's disease. It suggests that amantadine, often overlooked, might be a valuable first-line treatment option due to its effectiveness and safety profile. The author highlights amantadine's potential to mitigate levodopa-related dyskinesia and its lack of association with impulse control disorder.
Think About It Like a Desert Oasis
Imagine a thirsty traveler traversing the vast desert. A sudden oasis appears, offering relief from the scorching heat and dehydration. Similarly, amantadine, like a desert oasis, may offer a refreshing alternative for Parkinson's disease patients seeking relief from their symptoms without the risks associated with other medications.
Dr.Camel's Conclusion
This article presents a compelling case for revisiting the role of amantadine in the treatment of Parkinson's disease. The author provides evidence suggesting that amantadine, often ignored in the current debate, might be a valuable initial treatment option, offering potential benefits in terms of efficacy, safety, and lack of association with impulse control disorder.
Date :
- Date Completed 2022-02-16
- Date Revised 2022-02-16
Further Info :
Related Literature
English
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