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Case Report: Successful Long-Term Management of a Low-Birth Weight Preterm Infant With Compound Heterozygous Protein C Deficiency With Subcutaneous Protein C Concentrate Up to Adolescence.

Author: BeedgenBernd, BehnischWolfgang, KussNavina, PöschlJohannes

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.

Overview

This case study reports the successful management of a preterm infant with protein C deficiency, a condition that can lead to severe thrombotic complications. The infant received continuous intravenous and subcutaneous protein C concentrate therapy, followed by a switch to direct oral anticoagulants. This approach resulted in excellent quality of life for the child without any history of thrombosis for 13 years. The study also proposes early cesarean section at 32-34 weeks of gestation to reduce maternal and fetal complications.
Paper Details　
Original Abstract of the Article :
Homozygous/compound heterozygous forms of congenital protein C deficiency are often associated with severe antenatal and postnatal thrombotic or hemorrhagic complications. Protein C deficiency frequently leads to severe adverse outcomes like blindness and neurodevelopmental delay in children and may...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8506145/

データ提供：米国国立医学図書館（NLM）

A Premature Camel's Journey: Navigating Protein C Deficiency

This study delves into the world of protein C deficiency, a rare genetic disorder that affects blood clotting. Imagine a camel born prematurely in the desert, facing a long and challenging journey with a fragile system. This study follows a preterm infant with protein C deficiency, highlighting the importance of early intervention and tailored treatment.

A Tailored Oasis

The researchers describe a unique approach to managing protein C deficiency in this preterm infant, involving a combination of intravenous and subcutaneous protein C concentrate. This is like providing the premature camel with vital nutrients and hydration in the harshest of environments. The researchers also recommend early cesarean delivery to minimize complications for both mother and child.

Building a Sustainable Future

The study emphasizes the importance of lifelong treatment for individuals with protein C deficiency. The researchers demonstrate that with careful monitoring and customized therapy, individuals with this disorder can enjoy a healthy life. This is like providing the camel with a reliable water source and a safe path, allowing it to thrive in the desert.

Dr. Camel's Conclusion

The study offers a powerful testament to the resilience of life. By adapting to the challenges of protein C deficiency, the researchers provide a pathway for individuals with this disorder to navigate the desert of their condition and lead fulfilling lives.

Date :
  1. Date Completed n.d.
  2. Date Revised 2021-10-16
Further Info :

Pubmed ID

34650936

DOI: Digital Object Identifier

PMC8506145

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