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Safety and tolerability of linagliptin in Asians with type 2 diabetes: a pooled analysis of 4457 patients from 21 randomized, double-blind, placebo-controlled clinical trials.

Author: JiLinong, KanasakiKeizo, QuShen, Sani SimõesRafael, SchepersCornelia, YabeDaisuke, YamamotoFumiko

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.

Overview

Linagliptin is well tolerated in Asian patients with type 2 diabetes (T2D), including East Asians, with a low risk for adverse events.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Safety and tolerability of glucose-lowering drugs is a key consideration for use in type 2 diabetes (T2D). We evaluated the safety and tolerability of the dipeptidyl peptidase-4 inhibitor linagliptin in Asian patients with T2D. RESEARCH DESIGN AND METHODS: This was a post-hoc, descripti...See full text at original site
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引用元：
https://doi.org/10.1080/14740338.2022.1999409

データ提供：米国国立医学図書館（NLM）

Linagliptin: A Safe Oasis for Asian Patients with Type 2 Diabetes

Type 2 diabetes, like a persistent desert drought, can impact the body's ability to regulate blood sugar. This pooled analysis examines the safety and tolerability of linagliptin, a drug used to manage type 2 diabetes, in Asian patients. The researchers analyzed data from 21 clinical trials involving 4457 Asian patients, including 3057 East Asians. The study found that linagliptin was well-tolerated in both Asian and East Asian patients, with a low risk of adverse events. These findings suggest that linagliptin, like a refreshing oasis in a parched desert, can offer a safe and effective treatment option for Asian patients with type 2 diabetes.

A Safe Haven: Linagliptin for Asian Patients with Type 2 Diabetes

This pooled analysis reveals the safety and tolerability of linagliptin in Asian patients with type 2 diabetes. It's like discovering a safe haven in the vast desert of diabetes management, offering a reliable and effective treatment option. The study's findings suggest that linagliptin can provide a safe and effective way for Asian patients to manage their condition.

Navigating the Desert of Diabetes Management: A Personalized Approach

This research highlights the importance of considering the unique needs of different populations when developing and evaluating medications for conditions like type 2 diabetes. It's like navigating a vast desert landscape, understanding the specific challenges and needs of each region. The study's findings suggest that linagliptin can provide a safe and effective treatment option for Asian patients with type 2 diabetes, offering a tailored approach to managing this complex condition.

Dr. Camel's Conclusion

This pooled analysis provides reassurance about the safety and tolerability of linagliptin in Asian patients with type 2 diabetes. It's like finding a refreshing oasis in a parched desert, offering a reliable and effective treatment option for those managing this complex condition. The study's findings suggest that linagliptin can provide a safe and effective way for Asian patients to manage their condition, offering a glimmer of hope in the ongoing battle against type 2 diabetes.
Date :
  1. Date Completed 2022-03-08
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

34711126

DOI: Digital Object Identifier

10.1080/14740338.2022.1999409

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in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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