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Efficacy of narrow band UVB with or without OMP in stabilization of vitiligo activity in skin photo-types (III-V): A double-blind, randomized, placebo-controlled, prospective, multicenter study.

Author: AbdallahMarwa, Abdel-AzizRasha Ta, Abdel-GaberReham M, Abdel-HalimDalia, AnbarTag S, AttiaMiriam Samir, BassiounyDalia, EidAmira Abulfotooh, El HawaryMarwa, El-BassiounyMahy, El-HusseinyRania, El-MoftyMedhat, EsmatSamia M, FaridCarmen, FawzyMarwa M, GawdatHeba I, GenedyRasha Mahmoud, HegazyRehab, MogawerRania M, MostafaWedad Z, NassarAhmed, RagabNanis, RasheedH, SanyIman, ShalabySuzan, TawfikYasmin M

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Multicenter StudyResearch conducted in collaboration with multiple research institutions. It aims to collect a wide range of data and obtain more generalizable results.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study examined the effectiveness of narrowband ultraviolet B (NB-UVB) therapy in stabilizing vitiligo, highlighting the need for more randomized controlled trials to assess its efficacy in dark skin.
Paper Details　
Original Abstract of the Article :
NB-UVB has long been the vitiligo management pillar with capability of achieving the main treatment outcomes; repigmentation and stabilization. Its stabilizing effect in dark skin has been debatable. However, randomized controlled trials regarding NB-UVB ability to control disease activity are lacki...See full text at original site
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引用元：
https://doi.org/10.1111/phpp.12749

データ提供：米国国立医学図書館（NLM）

Narrowband UVB: A Pivotal Player in Vitiligo Management

Vitiligo, a skin condition characterized by patches of depigmentation, can be a challenging condition to treat. This study explores the use of narrowband UVB (NB-UVB) therapy, a mainstay treatment for vitiligo, with a focus on its ability to stabilize the condition in individuals with darker skin tones (skin photo-types III-V). This research is a double-blind, randomized, placebo-controlled study, providing a robust scientific approach to evaluate the effectiveness of NB-UVB therapy for stabilizing vitiligo in these specific skin photo-types. The study aimed to address a gap in the current understanding of NB-UVB's efficacy in individuals with darker skin, as previous research on its stabilizing effect has been limited.

Unveiling the Stabilizing Power of NB-UVB

The study highlights the potential of NB-UVB therapy in stabilizing vitiligo activity, particularly in individuals with darker skin tones. This finding is significant as it provides much-needed scientific evidence to support the effectiveness of NB-UVB therapy in this specific population.

Navigating the Path to Skin Health

This research provides valuable insights for individuals with vitiligo, especially those with darker skin tones. While this study focuses on the stabilizing effect of NB-UVB therapy, it's crucial to remember that managing vitiligo often involves a multi-faceted approach. Consulting with a dermatologist is essential to determine the most appropriate treatment plan for each individual case.

Dr. Camel's Conclusion

This study sheds light on the effectiveness of NB-UVB therapy in stabilizing vitiligo in individuals with darker skin tones. As a researcher, I am encouraged by this finding, as it underscores the continuous advancements in the field of dermatology. The journey to managing vitiligo can be long and challenging, but research like this provides hope and a roadmap for those seeking effective treatments.

Date :
  1. Date Completed 2022-05-11
  2. Date Revised 2022-05-11
Further Info :

Pubmed ID

34726808

DOI: Digital Object Identifier

10.1111/phpp.12749

Related Literature

Article Analysis
・Effective treatment of vitiligo
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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