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Real clinical impact of drug-drug interactions of immunosuppressants in transplant patients.

Author: AumenteMaría Dolores, CallejaMiguel Ángel, CárdenasManuel, Del PradoJosé Ramón, FontPilar, Gago-SánchezAna Isabel

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Observational StudyResearch that observes and collects data on participants' behavior and outcomes in their natural state, without intervention.

Overview

Real drug-drug interactions (DDIs) between immunosuppressants are prevalent in transplant patients, leading to adverse drug events. This highlights the importance of careful monitoring and management of DDI risks.
Paper Details　
Original Abstract of the Article :
The main objective was to determine the prevalence of real drug-drug interactions (DDIs) of immunosuppressants in transplant patients. We conducted a prospective, observational 1-year study at a tertiary hospital, including all transplanted patients. We evaluated data from monitoring blood concentra...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8578873/

データ提供：米国国立医学図書館（NLM）

Immunosuppressants and Drug Interactions: Navigating a Complex Landscape

The world of transplantation is a delicate dance, requiring meticulous balance to ensure success. This study delves into the intricate world of immunosuppressants and drug interactions, exploring the potential for adverse events in transplant patients.

Unveiling the Hidden Dangers: Real Drug Interactions in Transplant Patients

The study found that a significant percentage of transplant patients experience real drug-drug interactions (DDIs) involving immunosuppressants. The most common adverse event was nephrotoxicity, highlighting the importance of vigilant monitoring and careful management of drug combinations.

Protecting Transplant Recipients: Strategies for Minimizing Risk

This research provides valuable insights into the real clinical impact of DDIs in transplant patients. The findings underscore the need for careful drug selection, dose adjustments, and regular monitoring to minimize the risk of adverse events and ensure optimal patient outcomes.

Dr.Camel's Conclusion

The success of transplantation hinges on maintaining a delicate balance. This research emphasizes the importance of careful drug management and vigilant monitoring to navigate the complex landscape of immunosuppressants and drug interactions, ensuring the well-being of transplant recipients.

Date :
  1. Date Completed 2022-02-15
  2. Date Revised 2022-02-15
Further Info :

Pubmed ID

34755493

DOI: Digital Object Identifier

PMC8578873

SNS
PICO Info
in preparation
Languages

English

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