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Pharmacological and somatic treatment effects on suicide in adults: A systematic review and meta-analysis.

Author: Avila-QuinteroVictor J, BlochMichael H, FloresJosé M, KidambiAnubhav, OlfsonMark, RamirezKarina L, RheeT Greg, RuppZachary W, Trujillo DiazDaniel, WilkinsonSamuel T

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Meta-AnalysisA statistical technique that integrates the results of multiple studies to draw more general conclusions about a particular issue.
Research Support, N.I.H., ExtramuralResearch funding provided by the NIH to external research institutions and researchers.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.
Research Support, U.S. Gov't, P.H.S.Research funding provided by the Public Health Service (PHS).
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

Lithium and clozapine were consistently shown to reduce the risk of suicide in patients with bipolar disorder and psychotic disorders, respectively.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Suicide is a public health crisis. We conducted a systematic review and meta-analysis of the effects of psychopharmacologic and somatic therapies on suicide risk. METHODS: A systematic search of MEDLINE for studies evaluating the effects of pharmacologic (excluding antidepressants) or s...See full text at original site
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引用元：
https://doi.org/10.1002/da.23222

データ提供：米国国立医学図書館（NLM）

Pharmacological and Somatic Treatments for Suicide: A Comprehensive Review

This research takes us to the complex and often sensitive realm of suicide prevention. It’s a topic that requires careful consideration and a compassionate approach. This study examines the effects of pharmacological and somatic therapies on suicide risk in adults, aiming to shed light on the potential benefits and limitations of these interventions.

The researchers conducted a systematic review and meta-analysis of studies evaluating the effects of pharmacological and somatic interventions on suicide risk. They found that lithium was associated with a reduction in the odds of suicide in patients with bipolar disorder, and clozapine was associated with a reduction in the odds of suicide in patients with psychotic disorders. These findings suggest that these medications may offer potential benefits in preventing suicide in specific clinical contexts.

Finding Hope in the Desert of Suicide Prevention

This research provides valuable insights into the potential role of pharmacological and somatic therapies in reducing suicide risk. It’s a reminder that there is hope for individuals struggling with suicidal thoughts and that treatment options are available. It’s like finding a well of hope in the vast desert of despair, offering a lifeline to those seeking help.

Supporting Mental Well-being

This study underscores the importance of seeking professional help for mental health conditions and the need for comprehensive care, including both pharmacological and non-pharmacological interventions. It’s a reminder that we must work together to create a more supportive and compassionate environment for individuals struggling with suicidal thoughts.

Dr. Camel’s Conclusion

This study provides a comprehensive overview of the evidence regarding pharmacological and somatic treatments for suicide in adults. It highlights the potential benefits of certain medications, particularly lithium and clozapine, in reducing suicide risk in specific clinical contexts. This research is a testament to the ongoing efforts to understand and address the complex challenges of suicide prevention, emphasizing the importance of a multifaceted approach that addresses the needs of individuals struggling with suicidal thoughts and promotes mental well-being.
Date :
  1. Date Completed 2022-03-07
  2. Date Revised 2022-12-07
Further Info :

Pubmed ID

34762330

DOI: Digital Object Identifier

10.1002/da.23222

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・Effective treatment of suicide
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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