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Adverse effects associated with bupropion therapeutic errors in adults reported to four United States Poison Centers.

Author: AlwasiyahDalia, BassettRobert, BeuhlerMichael C, SpillerHenry A

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Single, unintentional bupropion ingestions in adults resulted in mostly mild outcomes and appeared to be dose-related. Home management may be an option for doses up to 900 mg in appropriate patients.
Paper Details　
Original Abstract of the Article :
CONTEXT: Bupropion is a frequently used medication. Excessive doses may cause altered mental status, seizures, and dysrhythmias. There is a need for accurate estimate of seizure risk with therapeutic errors and determination if minor symptoms are harbingers of more severe effects. METHODS: A retros...See full text at original site
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引用元：
https://doi.org/10.1080/15563650.2021.2002353

データ提供：米国国立医学図書館（NLM）

Navigating the Potential Risks of Bupropion Therapeutic Errors

The desert of medication errors can be a dangerous place, leading to unintended consequences. This study examines the adverse effects associated with bupropion therapeutic errors in adults, providing valuable insights into the potential risks associated with this commonly prescribed medication. The authors conducted a retrospective review of bupropion ingestions reported to four poison centers, analyzing the relationship between dose, patient characteristics, and adverse effects.

Understanding the Risks of Bupropion Overdose

The study found that outcomes from single unintentional bupropion ingestions in adults were generally mild and dose-related. The authors noted that while higher doses were associated with more severe adverse effects, such as seizures and dysrhythmias, the majority of cases resulted in no effect or only minor symptoms. This study serves as a reminder of the importance of careful medication management, emphasizing the need for accurate dosage and monitoring for potential adverse effects.

Patient Safety and Medication Management

This study underscores the importance of patient safety and medication management. The authors emphasize the need for healthcare providers to be aware of the potential risks associated with bupropion therapeutic errors, particularly in the context of overdose. The study highlights the importance of accurate dosage, careful monitoring, and prompt intervention in the event of adverse effects.

Dr. Camel's Conclusion

This study serves as a cautionary tale, reminding us of the potential risks associated with medication errors. The findings highlight the importance of accurate dosage, careful monitoring, and prompt intervention in the event of adverse effects, particularly in the case of bupropion. Think of it as traversing a vast desert of medication risks, taking precautions to avoid the dangerous mirages of therapeutic errors.
Date :
  1. Date Completed 2022-03-31
  2. Date Revised 2022-04-28
Further Info :

Pubmed ID

34812101

DOI: Digital Object Identifier

10.1080/15563650.2021.2002353

Related Literature

Article Analysis
・Side Effects of bupropion
SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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