Paper Details 
Original Abstract of the Article :
Influenza A virus, the main flu agent, affects billions of people worldwide. Conventional treatments still present limitations related to drug-resistance and severe side effects. As a result, natural product-derived molecules have been increasingly investigated as prospect drug candidates. Therefore...See full text at original site
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引用元:
https://doi.org/10.1590/0001-3765202120210964

データ提供:米国国立医学図書館(NLM)

Phytocompounds from Schinopsis brasiliensis: Potential Antiviral Agents Against Influenza A

The search for effective antiviral therapies against influenza A virus is as challenging as traversing a vast and unforgiving desert. This study investigated the antiviral potential of two phytocompounds, syringaresinol and cycloartenone, derived from the bark of Schinopsis brasiliensis, a tree native to South America. The researchers employed in silico approaches to evaluate the binding affinities of these compounds to key proteins involved in influenza A virus replication.

Promising Antiviral Activity of Phytocompounds

The study found that both syringaresinol and cycloartenone exhibited promising in silico antiviral activity against several influenza A proteins, including neuraminidase, polymerase basic protein 2, hemagglutinin, and the M2 ion channel protein. These findings, like a hidden oasis in the desert, offer a glimmer of hope for developing new antiviral therapies from natural sources.

Exploring Natural Antiviral Agents

This research, much like a desert expedition revealing hidden treasures, highlights the potential of natural products for combating viral infections. The study suggests that syringaresinol and cycloartenone warrant further investigation as potential antiviral agents, potentially paving the way for new and effective therapies for influenza A infection.

Dr.Camel's Conclusion

This study, like a camel caravan carrying valuable resources across the desert, offers a promising approach for combating influenza A virus. The findings suggest that syringaresinol and cycloartenone, derived from a natural source, exhibit significant antiviral activity, paving the way for the development of novel and potentially safer therapies for influenza A infection.

Date :
  1. Date Completed 2021-11-25
  2. Date Revised 2021-11-25
Further Info :

Pubmed ID

34817041

DOI: Digital Object Identifier

10.1590/0001-3765202120210964

Related Literature

SNS
PICO Info
in preparation
Languages

English

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