Short-course daily isoniazid and rifapentine for latent tuberculosis infection in people living with HIV who received coformulated bictegravir/emtricitabine/tenofovir alafenamide.

Author: ChengChih-Ning, ChuangYu-Chung, HungChien-Ching, KuoChing-Hua, LinKuan-Yin, LinShu-Wen, LinYa-Ting, LinYu-Jou, LiouBo-Huang, LiuWen-Chun, SunHsin-Yun

Paper Details 
Original Abstract of the Article :
Short-course preventive therapy with 1-month course of daily administration of isoniazid (300-mg) plus rifapentine (600-mg) (1HP) and 3-month course of weekly administration of isoniazid (900-mg) plus rifapentine (900-mg) (3HP) has higher completion rates than 9-month course of daily isoniazid (9H) ...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8614225/

データ提供:米国国立医学図書館(NLM)

Short-Course Daily Isoniazid and Rifapentine for Latent Tuberculosis Infection

The fight against tuberculosis (TB) is a long and arduous journey, much like traversing a vast desert. Researchers are constantly working to develop effective and convenient treatments for latent TB infection (LTBI). This study evaluated the effectiveness and safety of a short-course regimen of daily isoniazid (INH) and rifapentine (RPT) in people living with HIV (PLWH) who were receiving a combination therapy for HIV.

The study found that the short-course regimen of INH and RPT was well-tolerated and had a high completion rate, suggesting that it could be a viable alternative to the standard 9-month regimen of daily INH. The findings highlight the importance of exploring shorter treatment durations for LTBI, especially for PLWH, who may benefit from more convenient and effective treatment options.

Short-Course Treatment for Latent Tuberculosis Infection

This study provides compelling evidence for the effectiveness and safety of a short-course regimen of INH and RPT for LTBI in PLWH. It's like finding a shortcut through the desert of TB treatment, offering a more efficient and convenient path to preventing active TB.

Preventing Active Tuberculosis Infection

If you have LTBI, it's crucial to consult with your doctor to discuss the most appropriate treatment options. There are various approaches available, and finding the right one for you depends on your individual circumstances and health status. Remember, preventing active TB infection is like finding a safe oasis in the desert of infectious diseases. It's worth the effort to seek the right treatment and protect your health.

Dr. Camel's Conclusion

This study offers a promising new path in the fight against TB, particularly for PLWH. It's like discovering a hidden spring in the desert, offering a source of hope for those seeking effective and convenient treatment options.

Date :
  1. Date Completed 2021-12-03
  2. Date Revised 2021-12-14
Further Info :

Pubmed ID

34822220

DOI: Digital Object Identifier

PMC8614225

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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