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A randomised placebo-controlled clinical trial on the efficacy of local lidocaine injections and oral citalopram for the treatment of complex regional pain syndrome.

Author: FallicoNefer, PadmanabhanRahul, RahmanShakeel, SommaFrancesco, SpagnoliAnna Maria

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

This study evaluated the efficacy of a therapeutic protocol consisting of oral citalopram and lidocaine injections for treating complex regional pain syndrome (CRPS). The combined treatment was more effective than lidocaine alone or placebo in reducing CRPS severity.
Paper Details　
Original Abstract of the Article :
BACKGROUND: Complex regional pain syndrome (CRPS) is a neuropathic pain condition with no universally recognised treatment. The study evaluates the efficacy of a therapeutic protocol consisting of oral citalopram and lidocaine injections in patients affected by CRPS. METHODS: Between January 2010 a...See full text at original site
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引用元：
https://doi.org/10.1016/j.bjps.2021.11.022

データ提供：米国国立医学図書館（NLM）

A New Treatment Protocol for Complex Regional Pain Syndrome (CRPS)

Complex regional pain syndrome (CRPS) is a debilitating condition that can make even the simplest tasks feel like navigating a treacherous desert of pain. This research investigates the efficacy of a combination therapy using local lidocaine injections and oral citalopram in managing CRPS. The authors meticulously compared this combined approach to local anesthetic alone and placebo in a randomized, placebo-controlled clinical trial.

Combined Therapy Shows Promising Results for CRPS

The study reveals that the combined treatment of local lidocaine injections and oral citalopram demonstrated significantly greater effectiveness in reducing CRPS severity compared to local anesthetic alone or placebo. This finding suggests that this combined approach might be a valuable tool for managing this challenging condition.

Navigating the Complexities of Pain Management

This research highlights the importance of individualized and multi-modal approaches to pain management, acknowledging the complexities of chronic pain conditions. The study emphasizes the need for continued research to explore effective and safe treatment options for CRPS and other chronic pain conditions.

Dr.Camel's Conclusion

This study offers a beacon of hope in the vast desert of chronic pain management. It emphasizes the importance of exploring new and innovative approaches to treating complex pain conditions like CRPS, offering potential relief and improved quality of life for patients.

Date :
  1. Date Completed 2022-04-04
  2. Date Revised 2022-05-09
Further Info :

Pubmed ID

34903493

DOI: Digital Object Identifier

10.1016/j.bjps.2021.11.022

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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