Paper Details 
Original Abstract of the Article :
Since information of antiviral drug oseltamivir on the anti-atrial fibrillation (AF) property is still limited, we assessed it using the canine paroxysmal AF model. Oseltamivir in doses of 3 and 30 mg/kg/10 min was intravenously infused to the isoflurane-anesthetized, chronic atrioventricular block ...See full text at original site
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引用元:
https://doi.org/10.1016/j.jphs.2021.11.002

データ提供:米国国立医学図書館(NLM)

Oseltamivir's Hidden Talent: A Potential Anti-Atrial Fibrillation Drug

Oseltamivir, a well-known antiviral drug, often associated with treating influenza, has a hidden talent. This study delves into the intriguing possibility of repurposing this drug as a potential anti-atrial fibrillation (AF) treatment. The researchers used a canine model of paroxysmal AF to investigate the hemodynamic and electrophysiological effects of oseltamivir, unveiling a promising new role for this versatile drug.

Oseltamivir's Anti-AF Properties: A New Frontier in Heart Health

The study revealed that oseltamivir effectively reduced the incidence and duration of AF, demonstrating a dose-dependent effect. This finding opens the door to exploring oseltamivir's therapeutic potential in managing AF, a debilitating heart rhythm disorder affecting millions worldwide.

A Promising Future: Exploring the Potential of Oseltamivir

This research sheds light on the potential of oseltamivir to be repurposed as an anti-AF drug. The findings are a testament to the power of scientific inquiry in exploring novel therapeutic applications for existing drugs. Further research is needed to validate these findings in human trials, but the results offer a glimmer of hope for those battling AF, potentially leading to new and effective treatment options.

Dr. Camel's Conclusion

This study reveals the remarkable potential of oseltamivir to go beyond its traditional role as an antiviral drug and become a valuable tool for managing atrial fibrillation. This research journey reminds us that scientific exploration is a continuous desert trek, leading to unexpected oases of discovery. The potential of oseltamivir to combat this debilitating heart rhythm disorder is a testament to the power of scientific innovation in transforming healthcare.

Date :
  1. Date Completed 2022-02-10
  2. Date Revised 2022-02-10
Further Info :

Pubmed ID

34924124

DOI: Digital Object Identifier

10.1016/j.jphs.2021.11.002

Related Literature

SNS
PICO Info
in preparation
Languages

English

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