Efficacy, safety, and acceptability of polyethylene glycol 3350 without electrolytes vs magnesium hydroxide in functional constipation in children from six months to eighteen years of age: A controlled clinical trial.

Author: Valdez-ChávezL, Verdiguel-OyolaM, Vázquez-FriasR, Worona-DibnerL

Paper Details 
Original Abstract of the Article :
There are few studies that compare polyethylene glycol (PEG) 3350 and magnesium hydroxide (MH), as long-term treatment of functional constipation (FC) in children, and they do not include infants as young as 6 months of age. Our aim was to determine the efficacy, safety, and acceptability of PEG vs ...See full text at original site
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引用元:
https://doi.org/10.1016/j.rgmxen.2021.12.005

データ提供:米国国立医学図書館(NLM)

Polyethylene Glycol 3350 vs. Magnesium Hydroxide for Functional Constipation in Children

This research investigates the efficacy, safety, and acceptability of two commonly used treatments for functional constipation (FC) in children: polyethylene glycol (PEG) 3350 and magnesium hydroxide (MH). The researchers conducted a controlled clinical trial, comparing the long-term effects of these treatments in pediatric patients ranging from 6 months to 18 years of age. Their findings provide valuable information for clinicians seeking to optimize treatment options for children with FC.

PEG 3350: A Promising Option for Long-Term Functional Constipation Management

The study found that PEG 3350 was effective, safe, and acceptable for long-term treatment of FC in children, including infants as young as 6 months old. The researchers observed significantly improved bowel function and reduced constipation symptoms in children receiving PEG 3350 compared to those receiving MH. These findings suggest that PEG 3350 may be a preferred treatment option for FC in children, offering both efficacy and tolerability.

Optimizing Treatment for Functional Constipation in Children

This study highlights the importance of carefully considering treatment options for FC in children, selecting therapies that are both effective and well-tolerated. The researchers' findings suggest that PEG 3350 may be a promising option for long-term management of FC in pediatric patients, providing clinicians with a valuable tool for improving the well-being of children struggling with this condition.

Dr. Camel's Conclusion

This research reminds us that even in the vast and often challenging desert of pediatric gastrointestinal disorders, there are oases of hope. Understanding the nuances of FC treatment in children is crucial for optimizing their care, ensuring that they receive effective and safe therapies to improve their quality of life.

Date :
  1. Date Completed 2023-05-30
  2. Date Revised 2023-05-30
Further Info :

Pubmed ID

34961695

DOI: Digital Object Identifier

10.1016/j.rgmxen.2021.12.005

Related Literature

SNS
PICO Info
in preparation
Languages

English

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