Preoperative duloxetine on postoperative pain after laparoscopic gynecological surgeries: A systematic review and meta-analysis of randomized controlled trials.

Author: AbbasAhmed M, AbdelhakimAhmed Mohamed, AboshamaRehab Abdelhamid, Al-TounyAiman A, AlSghanRayan, AlkhamisWaleed H, AllamHassan Saleh, AlshahraniMajed Saeed, BaradwanSaeed, DaghashNoha H, DahshanShaimaa A, ElmazzalySaged Mohamed Metyli, Ezzat AbdelfattahLaila, FoudaAlbayoumi A, GhaziAhmed, IsmailReda A, RagabBassem

Paper Details 
Original Abstract of the Article :
OBJECTIVE: To evaluate the efficacy and safety of preoperative duloxetine on postoperative pain management after gynecologic laparoscopic surgeries. METHODS: A systematic search was done in Cochrane Library, PubMed, ISI web of science, and Scopus from inception to September 2021. We selected random...See full text at original site
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引用元:
https://doi.org/10.1016/j.jogoh.2021.102305

データ提供:米国国立医学図書館(NLM)

Preoperative Duloxetine: A Pain Relief Oasis for Gynecologic Surgeries

Navigating the world of postoperative pain is often a difficult journey, with patients seeking relief and clinicians striving for effective pain management. This meta-analysis explores the efficacy and safety of preoperative duloxetine for pain management after gynecologic laparoscopic surgeries. The researchers meticulously analyzed data from multiple randomized controlled trials (RCTs), comparing duloxetine to placebo.

Duloxetine: A Boon for Postoperative Pain

The meta-analysis revealed that duloxetine was associated with a significant reduction in pain scores at various time intervals post-surgery. Furthermore, patients receiving duloxetine required the first analgesic request later than those in the placebo group. Duloxetine also led to a significant decrease in postoperative analgesic consumption compared to placebo. Importantly, both groups displayed similar lengths of hospital stay and experienced comparable side effects.

A New Hope for Gynecologic Surgery Patients

The study's findings suggest that preoperative duloxetine is a safe and effective approach to managing postoperative pain after gynecologic laparoscopic surgeries. This research offers a promising strategy for improving patient comfort and well-being after surgery, potentially reducing the need for strong analgesics and minimizing side effects.

Dr.Camel's Conclusion

This study sheds light on the potential benefits of preoperative duloxetine in managing postoperative pain after gynecologic laparoscopic surgeries. The research provides valuable insights for clinicians seeking effective and safe pain management strategies for their patients. This finding is a welcome development in the quest to improve the postoperative experience for gynecologic surgery patients.

Date :
  1. Date Completed 2022-02-24
  2. Date Revised 2022-02-24
Further Info :

Pubmed ID

34974147

DOI: Digital Object Identifier

10.1016/j.jogoh.2021.102305

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SNS
PICO Info
in preparation
Languages

English

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