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Yellow fever vaccine usage in the United States and risk of neurotropic and viscerotropic disease: A retrospective cohort study using three healthcare databases.

Author: KhromavaAlena, LedlieShaleesa, LiLin, PanChunshen, RicciChristina, RojasAndrey

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

This study examined US civilian yellow fever vaccine usage, describing the population characteristics and pre-existing medical conditions of those vaccinated, and providing updated estimates of the risk of vaccine-associated neurotropic and viscerotropic disease.
Paper Details　
Original Abstract of the Article :
Yellow fever (YF) vaccines are highly effective and have a well-established safety profile despite the risk of rare serious adverse events (SAEs), vaccine-associated neurotropic (YEL-AND) and viscerotropic disease (YEL-AVD). This study aimed to describe US civilian YF vaccine usage, the population c...See full text at original site
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引用元：
https://doi.org/10.1016/j.vaccine.2021.12.047

データ提供：米国国立医学図書館（NLM）

Yellow Fever Vaccine Usage in the United States: A Comprehensive Look at Safety and Risk

In the vast and ever-changing desert of public health, we find ourselves navigating the delicate balance between vaccination and the potential for adverse events. This study, using three healthcare databases, provides a comprehensive analysis of yellow fever vaccine usage in the United States, examining the characteristics of vaccinated individuals, pre-existing conditions, and the risk of rare but serious adverse events such as vaccine-associated neurotropic (YEL-AND) and viscerotropic disease (YEL-AVD).

A Deep Dive into Yellow Fever Vaccine Usage and Risk Factors

The authors meticulously analyze the data, providing detailed insights into the population demographics, pre-existing medical conditions, and risk estimates for YEL-AND and YEL-AVD. This comprehensive analysis serves as a valuable resource for healthcare providers, enabling them to make informed decisions regarding yellow fever vaccination strategies.

Navigating the Risks: Balancing Protection and Potential Complications

While yellow fever vaccines offer significant protection against this potentially deadly disease, this study highlights the importance of considering potential risks, particularly in individuals with specific pre-existing conditions. This underscores the need for ongoing research and vigilance in monitoring vaccine safety and effectiveness to ensure optimal patient outcomes.

Dr.Camel's Conclusion

This study, like a guide through a treacherous desert, provides valuable insights into the complexities of yellow fever vaccination. It underscores the importance of a balanced approach, weighing the benefits of vaccination against the potential risks, particularly in individuals with pre-existing medical conditions. This research contributes to a deeper understanding of vaccine safety and the ongoing pursuit of public health initiatives.

Date :
  1. Date Completed 2022-01-26
  2. Date Revised 2022-01-26
Further Info :

Pubmed ID

34996642

DOI: Digital Object Identifier

10.1016/j.vaccine.2021.12.047

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Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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