Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice.

Author: HidaTetsuro, HiraiwaHideki, ImagamaShiro, IshiguroNaoki, IshizukaShinya, ItoKenyu, ItoMikako, KawamuraYusuke, KobayashiTakeshi, MasudaAkio, MatsushitaMasaki, NakashimaHiroaki, OhkawaraBisei, OhnoKinji, TanakaSatoshi, TsushimaMikito

Paper Details 
Original Abstract of the Article :
We screened pre-approved drugs for the survival of the Hu5/KD3 human myogenic progenitors. We found that meclozine, an anti-histamine drug that has long been used for motion sickness, promoted the proliferation and survival of Hu5/KD3 cells. Meclozine increased expression of MyoD, but reduced expres...See full text at original site
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引用元:
https://doi.org/10.1016/j.bbrc.2022.01.003

データ提供:米国国立医学図書館(NLM)

Meclozine: A Potential Hope for Muscular Dystrophy

This research journey takes us to the fascinating world of muscular dystrophy, where we find a potential oasis of hope in the form of meclozine, a drug commonly used for motion sickness. Researchers, like explorers navigating the vast desert of medical research, have discovered that meclozine, with its ability to promote the growth of myogenic progenitor cells, could potentially be a beacon of hope for those living with muscular dystrophy.

Meclozine's Promise for Muscle Regeneration

The findings of this study are like a refreshing spring in the desert, suggesting that meclozine could play a key role in improving muscle function. The researchers observed a significant improvement in muscle mass and exercise performance in mice with muscular dystrophy after meclozine treatment. This suggests that meclozine, like a benevolent desert wind, may be able to stimulate muscle regeneration and improve overall muscle health.

A Glimpse into a Potential Future Treatment

This exciting discovery opens a new avenue for research into the potential of meclozine as a therapeutic agent for muscular dystrophy. The findings, like a guiding star in the night sky, point towards the possibility of a new treatment approach, offering hope for a better future for those living with this debilitating condition.

Dr.Camel's Conclusion

This research is a testament to the enduring spirit of scientific exploration. Like intrepid explorers, researchers have discovered a potential oasis of hope in meclozine, a drug that could pave the way for new treatments for muscular dystrophy.

Date :
  1. Date Completed 2022-02-10
  2. Date Revised 2022-02-10
Further Info :

Pubmed ID

35033871

DOI: Digital Object Identifier

10.1016/j.bbrc.2022.01.003

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