Peppermint oil effects on the gut microbiome in children with functional abdominal pain.

Author: Abdel-RahmanSusan M, ChumpitaziBruno P, GargUttam, KearnsGregory L, LunaRuth Ann, MusaadSalma, OezguenNuman, ShulmanRobert J, ThapaSantosh, VersalovicJames

Paper Details 
Original Abstract of the Article :
Peppermint oil (PMO) is effective in the treatment of functional abdominal pain disorders, but its mechanism of action is unclear. Evidence suggests PMO has microbicidal activity. We investigated the effect of three different doses of PMO on gut microbiome composition. Thirty children (7-12 years of...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9010253/

データ提供:米国国立医学図書館(NLM)

Peppermint Oil's Impact on the Gut Microbiome in Children with Functional Abdominal Pain

The gut microbiome plays a crucial role in maintaining overall health and well-being. This study delves into the effects of peppermint oil (PMO) on the gut microbiome of children experiencing functional abdominal pain (FAP). PMO has shown promise in treating FAP, but its exact mechanism of action has remained elusive. The researchers investigated the impact of different PMO doses on the gut microbiome composition of children with FAP, providing valuable insights into the potential therapeutic benefits of PMO.

Unveiling the Subtle Effects of Peppermint Oil on the Gut Microbiome

The study revealed that while PMO did not significantly alter the overall bacterial composition of the gut microbiome, it did impact the abundance of certain low-abundance bacteria, particularly the Collinsella genus. This finding suggests that PMO might exert its therapeutic effects through subtle modifications of the gut microbiome, rather than causing dramatic shifts in the microbial landscape. The researchers observed a lower Firmicutes/Bacteroidetes ratio in children who received a higher PMO dose, hinting at a potential dose-dependent effect on the gut microbiome.

Peppermint Oil: A Promising Solution for Functional Abdominal Pain in Children

The study suggests that PMO may offer a safe and effective treatment option for children with FAP. However, further research is needed to determine the optimal dosage, duration of treatment, and long-term effects of PMO on the gut microbiome. As we delve deeper into the complex interplay between the gut microbiome and human health, understanding the mechanisms by which PMO influences gut microbiota holds significant potential for developing personalized therapies for FAP and other gut-related conditions.

Dr.Camel's Conclusion

This study is a fascinating exploration of the gut microbiome and its potential role in treating functional abdominal pain in children. It reminds us that even seemingly simple interventions like peppermint oil can have profound and unexpected effects on the complex ecosystem of our gut. The study's findings offer a glimpse into the future of personalized medicine, where tailored therapies can target specific aspects of the gut microbiome to address a wide range of health issues.

Date :
  1. Date Completed 2022-04-18
  2. Date Revised 2023-12-05
Further Info :

Pubmed ID

35048535

DOI: Digital Object Identifier

PMC9010253

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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