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A comparison of buprenorphine and pentazocine for the relief of postoperative pain.

Author: FreedmanM

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Controlled Clinical TrialA clinical trial that evaluates the effectiveness of a treatment by comparing a group that receives the intervention with a group that receives a placebo or standard treatment.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Buprenorphine (0.3 mg and 0.6 mg) and pentazocine (30 mg and 60 mg) were compared in 100 patients following orthopaedic surgery. Buprenorphine was more potent and had a longer duration of action than pentazocine. Buprenorphine was associated with less nausea, vomiting, and euphoria, but a higher incidence of sedation.
Paper Details　
Original Abstract of the Article :
The analgesic potency, efficacy, duration of action and side-effects of buprenorphine (Temgesic) 0.3 mg and 0.6 mg were compared with those of pentazocine (Sosegon) 30 mg and 60 mg in 100 male patients who had undergone orthopaedic surgical procedures. The drugs were given by intramuscular injection...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3510458

データ提供：米国国立医学図書館（NLM）

Comparing Analgesics for Postoperative Pain Relief

Postoperative pain is a common challenge, requiring effective analgesics to manage discomfort and promote recovery. It's like a camel experiencing a painful thorn after a long desert journey, needing relief and a way to heal. This study compares the effectiveness of buprenorphine and pentazocine for postoperative pain relief.

Buprenorphine: A More Potent and Long-Lasting Analgesic

The researchers found that buprenorphine was more potent and had a longer duration of action than pentazocine. It also resulted in less nausea, vomiting, and euphoria. However, buprenorphine was associated with a higher incidence of postoperative sedation. It's like finding a new type of cactus thorn remover that works more effectively but also causes a temporary feeling of drowsiness.

Choosing the Right Analgesic

The study highlights the need to carefully consider the potential benefits and drawbacks of different analgesics for postoperative pain management. It's like choosing the best tool for the job, considering the specific needs of the camel and the challenges of the desert journey.

Dr.Camel's Conclusion

This research provides valuable information about the relative effectiveness and side effects of buprenorphine and pentazocine for postoperative pain relief. The findings suggest that buprenorphine may be a more potent and longer-lasting analgesic option, but its sedative effects should be considered when making treatment decisions. It's like finding a way to make the desert journey more comfortable, but being mindful of the potential side effects of different remedies.

Date :
  1. Date Completed 1986-02-10
  2. Date Revised 2014-09-12
Further Info :

Pubmed ID

3510458

DOI: Digital Object Identifier

3510458

SNS
PICO Info
in preparation
Languages

English

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