HIV clinic-based extended-release naltrexone versus treatment as usual for people with HIV and opioid use disorder: a non-blinded, randomized non-inferiority trial.

Author: BachrachKen, BielavitzSarann, CollinsJulia A, CookRyan R, FanucchiLaura C, HoffmanKim A, JacobsPetra, JelstromEve, KorthuisP Todd, KunkelLynn E, LucasGregory M, LumPaula J, MatthewsAbigail, McCartyDennis, OdenNeal, PayneElizabeth H, RodriguezAllan E, SorensenJames L, TookesHansel, Vergara-RodriguezPamela, WaddellElizabeth Needham

Paper Details 
Original Abstract of the Article :
BACKGROUND AND AIM: Opioid agonist medications for treatment of opioid use disorder (OUD) can improve human immunodeficiency virus (HIV) outcomes and reduce opioid use. We tested whether outpatient antagonist treatment with naltrexone could achieve similar results. DESIGN: Open-label, non-inferiori...See full text at original site
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9314106/

データ提供:米国国立医学図書館(NLM)

Naltrexone: A New Oasis in the Desert of Opioid Use Disorder

The fight against opioid use disorder (OUD) is a challenging journey through a vast and unforgiving desert. This research examines the potential of extended-release naltrexone, an antagonist medication, as a promising treatment option for individuals with HIV and OUD. The study compared naltrexone to treatment as usual (TAU) with buprenorphine or methadone, finding that both treatments resulted in comparable rates of viral suppression and opioid use at 24 weeks. The findings suggest that naltrexone may offer a viable alternative for individuals seeking treatment for OUD, particularly for those who may not be able to access or tolerate opioid agonist therapies.

A Promising Alternative for OUD Treatment

The study suggests that extended-release naltrexone, an antagonist medication, may provide a viable treatment option for individuals with HIV and OUD. It's like discovering a new oasis in the desert, offering a fresh source of hope for those seeking effective treatment for their addiction. The findings encourage further research to explore the long-term effectiveness and safety of naltrexone in this population.

Navigating the Desert of Addiction Treatment

This research underscores the importance of providing diverse and individualized treatment options for individuals with OUD. It's like offering a range of paths through the desert, allowing individuals to choose the one that best suits their needs and preferences. The study highlights the potential benefits of extended-release naltrexone, but it's crucial for individuals to consult with their healthcare providers to discuss their specific needs and determine the most appropriate treatment plan. This research is a valuable step towards creating a more comprehensive and effective approach to managing OUD, offering a brighter future for those battling this challenging condition.

Dr. Camel's Conclusion

This study provides a glimmer of hope in the desert of opioid use disorder, highlighting the potential of extended-release naltrexone as a promising treatment option. The findings emphasize the need for a personalized approach to addiction treatment, allowing individuals to choose the path that best suits their needs. As we continue to explore innovative treatment strategies, we strive to create a more supportive and effective landscape for those navigating the challenging journey of recovery from OUD.

Date :
  1. Date Completed 2022-06-16
  2. Date Revised 2023-02-08
Further Info :

Pubmed ID

35129242

DOI: Digital Object Identifier

PMC9314106

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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