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Development of food-grade antimicrobials of fenugreek oil nanoemulsion-bioactivity and toxicity analysis.
Author: ChaudhariRamesh, KumarAshutosh, MansuriAbdulkhalik, MeghaniNikita, NasraSimran, RanjanShivendu
Original Abstract of the Article :
Antimicrobials of natural origin are proving to be an effective solution to emerging antimicrobial resistance and its physiological side effects. Recent studies have demonstrated that essential oils encapsulated in the form of nanoemulsions have better antimicrobial activity than the oil itself, pos...See full text at original site
Dr.Camel's Paper Summary Blogラクダ博士について
ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。
* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。
引用元:
https://doi.org/10.1007/s11356-022-19116-y
データ提供:米国国立医学図書館(NLM)
Fenugreek Oil Nanoemulsion: A Natural Antimicrobial with Potential
The rise of antimicrobial resistance poses a significant threat to global health. This research explores the potential of fenugreek oil nanoemulsion, a natural antimicrobial, as a potential alternative to synthetic antimicrobials. The authors fabricated nanoemulsions of fenugreek oil, a natural compound with antimicrobial and antioxidant properties, and investigated their bioactivity, antimicrobial properties, and toxicity against human hepatic cells. Their findings suggest that fenugreek oil nanoemulsions exhibit significant antimicrobial activity and have the potential to be used as safe and effective food-grade antimicrobials.
Fenugreek Oil Nanoemulsion: Antimicrobial Activity and Toxicity
The study found that fenugreek oil nanoemulsion exhibited significant antibacterial activity against a range of microbial strains, including Escherichia coli, Bacillus subtilis, Staphylococcus aureus, and Pseudomonas aeruginosa. Importantly, the nanoemulsion showed activity against P. aeruginosa, a bacterium known for its resistance to many antibiotics. Furthermore, the toxicity evaluation revealed that the nanoemulsion did not exhibit significant toxicity against human hepatic cells, suggesting its potential for safe use as a food-grade antimicrobial.
Implications for Food Safety and Antimicrobial Development
The study's findings offer a promising lead for the development of safe and effective natural antimicrobials. Fenugreek oil nanoemulsion demonstrates potential for use as a food-grade antimicrobial, addressing the growing challenge of antimicrobial resistance and offering a natural alternative to synthetic antimicrobials. Further research is needed to explore the potential applications of fenugreek oil nanoemulsion in food preservation and other areas where antimicrobial activity is required.
Dr.Camel's Conclusion
The desert is a rich source of natural resources, and this research highlights the potential of fenugreek oil as a powerful weapon against antimicrobial resistance. Like a camel traversing the desert, seeking out hidden springs of water, researchers are exploring the potential of natural compounds to combat the growing threat of drug-resistant microbes. This study offers a promising new avenue for the development of safe and effective natural antimicrobials, potentially revolutionizing the way we manage infections and protect our health.
Date :
- Date Completed 2023-03-10
- Date Revised 2023-03-10
Further Info :
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