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Amantadine-induced bilateral corneal edema in a pediatric patient.

Author: BohraLisa, ChaoJonathan, DunnSteven

Case ReportsIn the medical field, a report that describes in detail a unique case, an unusual medical condition, or the effect of a treatment. Provides new insights and possibilities for treatment through individual patient cases.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Amantadine, a drug primarily used for influenza A, is also used off-label for various neurological conditions. This case report describes a patient who experienced transient visual impairment associated with amantadine use, leading to regression of his underlying neurodevelopmental status. While amantadine-associated ocular side effects are rare, this case emphasizes the need for careful monitoring of patients on amantadine therapy.
Paper Details　
Original Abstract of the Article :
Amantadine was originally developed as an antiviral agent for influenza A. However, it also has off-label uses for Parkinson disease, multiple sclerosis, and in the management of extrapyramidal symptoms. The mechanism of action in these conditions has yet to be elucidated. Ocular side effects from s...See full text at original site
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引用元：
https://doi.org/10.1016/j.jaapos.2022.01.005

データ提供：米国国立医学図書館（NLM）

Amantadine-Induced Corneal Edema: A Rare Oasis in the Desert of Ocular Side Effects

Amantadine, a medication commonly used to treat conditions like Parkinson's disease and multiple sclerosis, can sometimes cause unexpected side effects. This research explores a rare but serious side effect of amantadine: bilateral corneal edema, a condition that can affect vision. The researchers present a case study highlighting this unusual side effect and the importance of recognizing potential complications associated with medications.

A Reminder of the Complexities of Medicine

The researchers highlight the importance of monitoring patients for potential side effects, even those considered rare. This case study serves as a reminder of the complexities of medicine and the need for vigilant observation to ensure patient safety. While amantadine is generally a safe and effective medication, this case underscores the importance of being aware of its potential risks and taking appropriate precautions.

Navigating the Desert of Ocular Side Effects

This research is a valuable reminder of the need to consider the potential for ocular side effects when prescribing medications, even those with a generally favorable safety profile. It highlights the importance of recognizing and promptly addressing any unusual symptoms that may arise, ensuring the well-being of patients. This research also encourages further research into the mechanisms underlying these rare side effects, contributing to our understanding of the complex interplay between medications and the human body.

Dr.Camel's Conclusion

This case study serves as a valuable reminder that even in the vast desert of medical knowledge, there are still hidden oases waiting to be discovered. By being vigilant about potential side effects, we can better protect the health and well-being of our patients. This research emphasizes the importance of continued research and careful monitoring to ensure patient safety and optimize the effectiveness of medications.

Date :
  1. Date Completed 2022-07-07
  2. Date Revised 2022-09-14
Further Info :

Pubmed ID

35151873

DOI: Digital Object Identifier

10.1016/j.jaapos.2022.01.005

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in preparation
Languages

English

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