The antiemetic efficacy of secobarbital and chlorpromazine compared to metoclopramide, diphenhydramine, and dexamethasone. A randomized trial.

Author: BatemanM, FlaumM A, KardinalC G, RichardsP D

Paper Details 
Original Abstract of the Article :
The efficacy of secobarbital sodium plus chlorpromazine (SC) in the prevention of cisplatin induced emesis was compared to the combination of metoclopramide, diphenhydramine, and dexamethasone (MDD). Twenty-three patients were entered onto protocol. Eighteen were evaluable. Good to excellent antieme...See full text at original site
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引用元:
https://doi.org/10.1002/1097-0142(19860815)58:4<959::aid-cncr2820580426>3.0.co;2-z

データ提供:米国国立医学図書館(NLM)

Antiemetic Efficacy: Finding a Oasis in the Desert of Nausea

Nausea and vomiting are common side effects of cancer treatments, making the journey through this challenging experience even more difficult. This study explores the antiemetic efficacy of various drug combinations in preventing cisplatin-induced emesis. The researchers compared the effectiveness of secobarbital sodium plus chlorpromazine (SC) to a combination of metoclopramide, diphenhydramine, and dexamethasone (MDD). They found that MDD was significantly more effective in preventing emesis, providing a much-needed oasis of relief for patients undergoing chemotherapy. This research is like finding a hidden spring of water in the desert of nausea, offering a new path toward managing this debilitating side effect.

MDD: A Promising Oasis in the Desert of Chemotherapy

The study found that the drug combination of metoclopramide, diphenhydramine, and dexamethasone (MDD) was significantly more effective in preventing cisplatin-induced emesis compared to secobarbital sodium plus chlorpromazine (SC). This is a crucial discovery, as it provides a more effective solution for managing this distressing side effect of chemotherapy. It's like finding a hidden oasis in the desert of chemotherapy, offering a haven from the discomfort of nausea and vomiting.

Navigating the Desert of Cancer Treatment

This research highlights the importance of exploring new and effective antiemetic therapies for patients undergoing cancer treatment. It's a reminder that the desert of cancer treatment is often fraught with challenges, and finding ways to alleviate suffering is essential. This study encourages us to continue seeking out new and innovative solutions to improve the lives of patients battling cancer, ensuring they have access to the best possible care and support during their journey.

Dr. Camel's Conclusion

This research takes us on a journey through the desert of nausea and vomiting, a common challenge for those undergoing cancer treatment. The study reveals the effectiveness of MDD in preventing emesis, offering a much-needed oasis of relief for patients. It's a reminder that the quest for better care in the desert of medicine is ongoing, and we must continue to seek out new and innovative solutions to improve the lives of those facing challenging illnesses.

Date :
  1. Date Completed 1986-08-21
  2. Date Revised 2019-06-19
Further Info :

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