Paper Details

  1. Home
  2. Paper Details

Effects of combined probucol-colestipol treatment for familial hypercholesterolemia and coronary artery disease.

Author: KostisJ B, KuoP T, MoreyraA E, WilsonA C

Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

Combined probucol-colestipol therapy plus diet was effective in treating familial hypercholesterolemia and coronary artery disease. The combination therapy stabilized the progression of existing lesions and prevented the formation of new lesions.
Paper Details　
Original Abstract of the Article :
To evaluate the effect of hypercholesterolemic treatment on coronary artery disease in patients known to be susceptible to disease progression, 44 patients with familial hypercholesterolemia and coronary artery disease were started on a lipid-lowering diet and either probucol (1 g/day) or colestipol...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://doi.org/10.1016/0002-9149(86)90437-6

データ提供：米国国立医学図書館（NLM）

Combating Familial Hypercholesterolemia: A Two-Pronged Approach

The challenge of managing familial hypercholesterolemia, a hereditary condition characterized by high cholesterol levels, requires multifaceted strategies. This study investigates the combined effects of probucol and colestipol, two lipid-lowering drugs, in patients with familial hypercholesterolemia and coronary artery disease. The research aims to evaluate the effectiveness of this combination therapy in preventing disease progression.

A Combined Approach to Lowering Cholesterol

This study showcases the benefits of a two-pronged approach to managing familial hypercholesterolemia. The research demonstrates that combining probucol and colestipol can effectively reduce cholesterol levels and potentially slow down the progression of coronary artery disease. This information highlights the importance of individualized treatment strategies for patients with this condition.

Guiding Your Way Through the Desert of High Cholesterol

This study is like a compass pointing us towards a healthier path for managing familial hypercholesterolemia. The research underscores the importance of a balanced diet and the potential benefits of specific medications in lowering cholesterol levels and reducing the risk of heart disease. Remember, as with any medical treatment, it's essential to consult with your doctor to discuss your individual needs and potential risks.

Dr.Camel's Conclusion

This study is a testament to the power of combining knowledge and resources to combat a challenging health condition. The research highlights the potential benefits of a two-pronged approach to managing familial hypercholesterolemia, offering hope for patients seeking to reduce their risk of heart disease.

Date :
  1. Date Completed 1986-07-31
  2. Date Revised 2019-06-22
Further Info :

Pubmed ID

3524177

DOI: Digital Object Identifier

10.1016/0002-9149(86)90437-6

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.