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Cimetidine for erythropoietic protoporphyria.
Author: HeerfordtIda M, LercheCatharina M, WulfHans Christian
Original Abstract of the Article :
Erythropoietic protoporphyria (EPP) is caused by deficiency of the enzyme converting protoporphyrin IX (PpIX) into heme resulting in accumulation of PpIX; leading to photosensitivity and liver toxicity. Cimetidine might inhibit δ-aminolevulinic acid synthase influencing the heme biosynthesis. We pre...See full text at original site
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引用元:
https://doi.org/10.1016/j.pdpdt.2022.102793
データ提供:米国国立医学図書館(NLM)
Cimetidine: A Potential Treatment for Erythropoietic Protoporphyria
Erythropoietic protoporphyria (EPP) is a rare genetic disorder that causes a buildup of protoporphyrin IX (PpIX), a molecule involved in heme production. This buildup leads to photosensitivity and liver toxicity. This research explores the potential of cimetidine, a medication commonly used for treating ulcers, as a treatment for EPP. The study presents cases of EPP patients treated with cimetidine and reviews the existing literature on this topic.
Cimetidine: A New Hope for EPP Patients?
This study suggests that cimetidine may offer a potential treatment option for EPP, providing a glimmer of hope for patients seeking relief from the debilitating symptoms of this disorder. The study highlights cimetidine's potential to influence heme biosynthesis, reducing the buildup of PpIX and potentially alleviating the symptoms of EPP.
Cimetidine: A Potential Solution for a Challenging Disorder
This research offers hope for individuals struggling with EPP, highlighting the potential of cimetidine as a treatment option. Further research is necessary to fully understand the effectiveness and safety of cimetidine for EPP. However, this study provides a promising direction for future investigations into this rare and challenging disorder.
Dr.Camel's Conclusion
Like a camel finding a hidden spring in the desert, this research uncovers a potential treatment for EPP. Cimetidine, a medication traditionally used for ulcers, could offer a new hope for those affected by this rare and challenging disorder. While more research is needed to confirm its effectiveness, this study suggests that there may be an oasis of relief for EPP patients.
Date :
- Date Completed 2022-06-08
- Date Revised 2022-06-08
Further Info :
Related Literature
English
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