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Application Site Reactions from the Buprenorphine Transdermal Patch: A Case Series.

Author: FudinJeffrey, MendozaKelly, Meyer-JuncoLaura, ReaBradlee

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.

Overview

This case series describes four patients who experienced skin reactions to buprenorphine transdermal patches (BTP). The reactions occurred at higher patch strengths and were suggestive of allergic hypersensitivity. However, some patients tolerated buprenorphine buccal films.
Paper Details　
Original Abstract of the Article :
Buprenorphine is a partial mu-opioid agonist available as a transdermal patch for use in patients with chronic pain. Transdermal products can be associated with application site reactions (ASRs). The incidence of ASRs to the buprenorphine transdermal patch (BTP) have been described as low and seldom...See full text at original site
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引用元：
https://doi.org/10.1080/15360288.2022.2051676

データ提供：米国国立医学図書館（NLM）

Application Site Reactions from the Buprenorphine Transdermal Patch

This study investigates the occurrence of application site reactions (ASRs) associated with the buprenorphine transdermal patch (BTP), a common medication for chronic pain. The researchers report a series of four patients who developed ASRs to the BTP, leading to treatment discontinuation or a switch to buprenorphine buccal films. They found that ASRs were more likely to occur at higher patch strengths, suggesting a potential dose-response relationship and a possible allergic reaction. This study provides valuable insights into the potential adverse effects of the BTP.

Application Site Reactions to Buprenorphine Patches

The study's findings highlight the potential for application site reactions (ASRs) to the buprenorphine transdermal patch (BTP), particularly at higher patch strengths. The researchers report a series of cases where ASRs led to treatment discontinuation or a switch to alternative medications. This information is important for healthcare providers to consider when prescribing BTP and for patients to be aware of potential side effects.

Managing Pain Without Side Effects

Imagine a camel carrying heavy loads across a rugged desert terrain. Just as the camel relies on its strength and endurance to overcome the challenges, individuals with chronic pain need effective pain management solutions. This study emphasizes the importance of carefully monitoring for ASRs when using buprenorphine patches. Understanding these potential side effects can help ensure that patients receive safe and effective pain relief.

Dr.Camel's Conclusion

This case series provides valuable insights into the potential for application site reactions (ASRs) associated with the buprenorphine transdermal patch (BTP). The findings suggest a potential dose-response relationship and a possible allergic reaction, highlighting the importance of monitoring for ASRs and considering alternative medications if they occur. Further research is needed to fully understand the mechanisms behind ASRs to the BTP.
Date :
  1. Date Completed 2022-05-02
  2. Date Revised 2022-05-02
Further Info :

Pubmed ID

35332848

DOI: Digital Object Identifier

10.1080/15360288.2022.2051676

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PICO Info
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Languages

English

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