Paper Details 
Original Abstract of the Article :
Benzimidazoles are the only approved drugs for the treatment of inoperable human alveolar echinococcosis but may be limited due to intolerance or, rarely, ineffectiveness. A medical second-line or salvage therapy is not available, though it is urgently needed. We report long-term follow-up data from...See full text at original site
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ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

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* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
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引用元:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8949663/

データ提供:米国国立医学図書館(NLM)

Salvage Therapy for Alveolar Echinococcosis: A Challenging Journey

This study examines the challenges of treating alveolar echinococcosis (AE), a rare parasitic infection, when standard therapies fail. The authors analyze the use of repurposed drugs as a ‘salvage therapy’ for patients who are unresponsive or intolerant to the standard treatment, benzimidazoles. This research highlights the importance of exploring new avenues for treating complex and difficult-to-manage diseases.

Repurposed Drugs: A Promising But Uncertain Approach

The study found that some repurposed drugs, such as amphotericin B and nitazoxanide, showed potential for treating AE, but with varying degrees of efficacy and significant side effects. The results underscore the need for cautious and individualized approaches when using these drugs.

Navigating the Uncertainty of Salvage Therapy

This study illustrates the challenging nature of salvage therapy for AE. Like exploring a vast and uncharted desert, finding effective treatments for these rare and complex conditions requires a combination of perseverance, innovation, and careful observation. This research provides valuable insights into the current landscape of salvage therapy for AE and emphasizes the need for further research.

Dr. Camel's Conclusion

This study shines a light on the difficult journey of finding effective treatments for rare and complex diseases like AE. The use of repurposed drugs presents a promising avenue but also highlights the inherent uncertainty and challenges of salvage therapy. It reminds us that even in the most challenging deserts of medicine, we must continue to seek new paths and solutions.

Date :
  1. Date Completed n.d.
  2. Date Revised 2022-03-29
Further Info :

Pubmed ID

35335657

DOI: Digital Object Identifier

PMC8949663

Related Literature

SNS
PICO Info
in preparation
Languages

English

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