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Captopril/hydrochlorothiazide combination in elderly patients with mild-moderate hypertension. A double-blind, randomized, placebo-controlled study.

Author: BaulacL, CreissonC, LenfantB

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

A fixed combination of captopril and hydrochlorothiazide was effective and safe in treating mild to moderate hypertension in elderly patients.
Paper Details　
Original Abstract of the Article :
Fifty-six elderly patients (mean age 72.1 +/- 4.1 years; mean creatinine 111.0 +/- 9.8 mumol/l were randomly assigned to either captopril (C) hydrochlorothiazide (HCT) fixed combination once daily (o.d.) (n = 29) or placebo (n = 27). Previous medication was stopped and following a run-in period of 2...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/3534849

データ提供：米国国立医学図書館（NLM）

Captopril/Hydrochlorothiazide: A Safe and Effective Treatment for Hypertension

Dr. Camel's interest in cardiovascular health has led him to explore the treatment of hypertension, and this study investigates the efficacy and safety of a fixed-dose combination of captopril and hydrochlorothiazide in elderly patients with mild-to-moderate hypertension. Researchers compared the blood pressure control and side effects of this combination to those of a placebo. This study aimed to assess the effectiveness and safety of this combination therapy for managing hypertension in elderly patients.

The Benefits of Captopril/Hydrochlorothiazide Combination Therapy

The study found that the captopril/hydrochlorothiazide combination effectively lowered blood pressure in elderly patients with mild-to-moderate hypertension and was well tolerated. These findings suggest that this combination therapy may be a safe and effective treatment option for managing hypertension in this patient population. This research highlights the potential benefits of fixed-dose combinations in simplifying medication regimens and improving patient adherence to treatment.

Managing Hypertension

Dr. Camel encourages individuals with hypertension to consult with their healthcare providers to discuss appropriate treatment options. A healthcare professional can assess your individual risk factors, monitor your blood pressure, and recommend a personalized treatment plan, which may include lifestyle modifications, medication, or a combination of both. This study underscores the importance of regular blood pressure monitoring and adhering to prescribed treatment plans for managing hypertension effectively.

Dr. Camel's Conclusion

Dr. Camel is impressed by the effectiveness and safety of the captopril/hydrochlorothiazide combination therapy for hypertension in elderly patients. This research highlights the importance of finding safe and effective treatment options for managing chronic conditions like hypertension. Dr. Camel encourages individuals to work closely with their healthcare providers to develop personalized treatment plans that address their specific needs and to prioritize healthy habits to manage their health effectively.

Date :
  1. Date Completed 1986-12-05
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

3534849

DOI: Digital Object Identifier

3534849

SNS
PICO Info
in preparation
Languages

English

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